2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.

Liposome Related Products (1007):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W440706
    Cholesterol-PEG2000-alcohol
    		99.91%
    Cholesterol-PEG2000-alcohol is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. The amine can react with an activated NHS ester to form a stable amide bond.
    Cholesterol-PEG2000-alcohol
  • HY-W440813
    Heptadecan-9-yl 8-bromooctanoate
    Heptadecan-9-yl 8-bromooctanoate can be useful for the building or modification of lipid nanoparticles.
    Heptadecan-9-yl 8-bromooctanoate
  • HY-W800784
    23:2 Diyne PE [DC(8,9)PE]
    23:2 Diyne PE [DC(8,9)PE] is a phospholipase-mediated hydrolyzed phosphocoline with palmitic acid (16:0) and Pentacosa-10,12-diynoic acid for tails.
    23:2 Diyne PE [DC(8,9)PE]
  • HY-155934
    18:1 PEG5000 PE ammonium
    		99.8%
    18:1 PEG5000 PE ammonium (DOPE-PEG5000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
    18:1 PEG5000 PE ammonium
  • HY-156616
    VC1052
    		99.72%
    VC1052 is a dialkoxypropylammonium-based material and is the core cationic lipid component of the cationic lipid adjuvant Vaxfectin (HY-142998). Vaxfectin consists of VC1052 and lipid DPyPE (HY-112766) in a 1:1 molar ratio. Vaxfectin can be used as a vaccine adjuvant for the preparation of plasmid DNA and protein vaccines.
    VC1052
  • HY-182100B
    DSPE-PEG3400-MTP
    DSPE-PEG3400-MTP is a PEG compound which composed of DSPE and a muscle-targeting peptide (MTP). MTP is a muscle-targeting peptide with the property of targeting muscle tissue. DSPE-PEG3400-MTP can be used for drug delivery.
    DSPE-PEG3400-MTP
  • HY-172279B
    DSPE-PEG5000-TAT
    DSPE-PEG5000-TAT is a PEG compound which composed of DSPE and a cell-penetrating peptide (TAT) (HY-P0281). DSPE-PEG5000-TAT can be used for drug delivery.
    DSPE-PEG5000-TAT
  • HY-403699
    LP-371-p
    		98.07%
    LP-371-p is a lipid that can specifically and efficiently deliver oligonucleotide compounds to the fat tissues in the body (especially fat cells). LP-371-p can be used in research on diseases related to fat, such as obesity and type 2 diabetes.
    LP-371-p
  • HY-159855
    CAP 2 hydrochloride
    CAP 2 (Cholesterol-amino-phosphate 2) hydrochloride is Cholesterol-amino-phosphate (CAP) lipid. CAP 2 can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads.
    CAP 2 hydrochloride
  • HY-W343736
    1,3-Dipalmitoyl-glycero-2-phosphoethanolamine
    		≥99.0%
    1,3-Dipalmitoyl-glycero-2-phosphoethanolamine is a phospholipid containing the saturated long-chain (16:0) stearic acid inserted at the sn-1 and sn-3 positions and PE at the sn-2 site. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
    1,3-Dipalmitoyl-glycero-2-phosphoethanolamine
  • HY-182095A
    DSPE-PEG2000-CTP
    DSPE-PEG2000-CTP is a PEG compound which composed of DSPE and a Cardiac-targeting peptide CTP (HY-P4094). CTP molecules that specifically recognize cardiac tissue and is primarily used for targeted drug delivery. CTP effectively recognizes and binds to specific receptors on the surface of cardiac cells, thereby achieving precise localization of drug molecules. DSPE-PEG2000-CTP can be used for drug delivery.
    DSPE-PEG2000-CTP
  • HY-159715
    Lipid DIM1
    		99.0%
    Lipid DIM1 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid DIM1 is a carrier for both siRNA and mRNA.
    Lipid DIM1
  • HY-W127528
    Cholesterol nervonate
    		99.7%
    Cholesterol nervonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Cholesterol nervonate
  • HY-N16102
    13:0 Lyso PE
    		99%
    13:0 Lyso PE is an intermediate. 13:0 Lyso PE can be used to synthesize tumor-triggered, targeted ammonium bicarbonate liposomes.
    13:0 Lyso PE
  • HY-W441009C
    DSPE-PEG4000-Maleimide ammonium
    DSPE-PEG4000-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG4000-Maleimide ammonium can be used in drug delivery research.
    DSPE-PEG4000-Maleimide ammonium
  • HY-167003
    L16
    		99.69%
    L16 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. L16 can be used in the preparation of liposomes.
    L16
  • HY-W800776
    DORI
    DORI is a cationic lipid that can deliver plasmid DNA in vitro. DORI has lower cytotoxicity and high transfection efficiency.
    DORI
  • HY-167011
    Al-28
    Al-28 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. Al-28 can be used in the preparation of liposomes.
    Al-28
  • HY-145798
    N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide
    		98.0%
    N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide is an analogue of TT3 (HY-148049). TT3 is an ionizable lipid-like materials for mRNA delivery.
    N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide
  • HY-144012H
    DPPE-PEG5000
    		99.94%
    DPPE-PEG5000 (16:0 PEG5000 PE) is a polymer-lipid conjugate and LipoParticle stabilizer with a PEG chain of 5,000 g/mol molecular weight attached to its polar head, and it can be internalized by biological membranes. DPPE-PEG5000 enables LipoParticle to maintain colloidal stability after 20-fold dilution in PBS or cell culture medium, and prevents aggregate formation during lyophilization and rehydration. DPPE-PEG5000 helps enhance the non-cytotoxic property of LipoParticle formulations against human osteoblasts. DPPE-PEG5000 serves as a PEG lipid functional end group for synthesizing liposomes (LPs), is used in the design of conjugated polymer nanoparticles, and applies to research related to bone and joint infections.
    DPPE-PEG5000