2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.

Liposome Related Products (1007):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-112764GL
    DMG-PEG 2000 (GMP Like)
    DMG-PEG 2000 (GMP Like) is DMG-PEG 2000 (HY-112764) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles.
    DMG-PEG 2000 (GMP Like)
  • HY-142986
    Dlin-MeOH
    Dlin-MeOH is a lipid product for use in drug delivery systems.
    Dlin-MeOH
  • HY-167004
    IAJD93
    		99.9%
    IAJD93 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. IAJD93 can be used in the preparation of liposomes.
    IAJD93
  • HY-172687
    DSPE-PEG2000-CSTSMLKAC
    DSPE-PEG2000-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). DSPE-PEG2000-CSTSMLKAC can be used for drug delivery DSPE-PEG2000-CSTSMLKAC enables targeted delivery of associated nanoliposomes to ischemic myocardial cells.
    DSPE-PEG2000-CSTSMLKAC
  • HY-142991
    1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol
    1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol (POPG) is an anionic phosphatidylglycerol that often serves as a key component to co-construct model phospholipid bilayers with phosphatidylcholine (e.g., at a 3:1 POPC:POPG ratio) for investigating the structure and dynamics of transmembrane proteins. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol acts as a fundamental material for mimicking the physicochemical properties of biological membranes and enables the elucidation of membrane protein interaction mechanisms.
    1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol
  • HY-172691
    DSPE-PEG5000-THRPPMWSPVWP
    DSPE-PEG5000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells.
    DSPE-PEG5000-THRPPMWSPVWP
  • HY-172509
    N-Tetradecyl-pSar25
    		99.88%
    N-Tetradecyl-pSar25 (Compound C14-pSar25) is a polysarcosine (pSar) lipid. PSar lipids exhibit maintained or even enhanced LNP transfection efficiency.
    N-Tetradecyl-pSar25
  • HY-172497
    DSPE-PEG2000-Mal-Cys-REKA
    DSPE-PEG2000-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG2000-CREKA can be used for drug delivery.
    DSPE-PEG2000-Mal-Cys-REKA
  • HY-W800825
    Octadecanedioic acid mono-L-carnitine ester
    Octadecanedioic Acid Mono-L-carnitine ester is a cationic lipid which may be used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Its terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond.
    Octadecanedioic acid mono-L-carnitine ester
  • HY-172699A
    DSPE-PEG3400-ANG
    DSPE-PEG3400-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG3400-ANG can be used for drug delivery.
    DSPE-PEG3400-ANG
  • HY-182101A
    DSPE-PEG2000-VHPKQHRGGSKGC
    DSPE-PEG2000-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a muscle-targeting peptide VHPKQHRGGSKGC (HY-P11088). GNYTCEVTELTREGETIIELK is a peptide that can bind to VCAM1. DSPE-PEG2000-GNYTCEVTELTREGETIIELK can be used for drug delivery.
    DSPE-PEG2000-VHPKQHRGGSKGC
  • HY-W127457
    1,2-Dihexanoyl-sn-glycero-3-phosphocholine
    		99.93%
    1,2-dihexanoyl-sn-glycero-3-phosphocholine is a phosphatidylcholine. It can play a role as a surfactant and is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.
    1,2-Dihexanoyl-sn-glycero-3-phosphocholine
  • HY-177843
    Liposomal NMN
    Liposomal NMN is a specialized delivery system that encapsulates NMN within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of NMN. NMN (β-Nicotinamide Mononucleotide) is a naturally occurring key met
    Liposomal NMN
  • HY-W441005
    Amino-Gly-Gly-DSPE hydrochloride
    Amino-Gly-Gly-DSPE (hydrochloride) is a specially modified phospholipid that has been used to synthesize liposomes. The terminal amine is reactive with an NHS ester compound or carboxylic acid molecule in the presence of activator, such as HATU or EDC.
    Amino-Gly-Gly-DSPE hydrochloride
  • HY-W250183B
    Polyoxyethylene (20) stearyl ether
    Polyoxyethylene (20) stearyl ether (Polyethylene glycol octadecyl ether (n～20)) is a PEGylated lipid surfactant. Polyoxyethylene (20) stearyl ether is used in studies on the formation and stabilization of lipid nanoparticles.
    Polyoxyethylene (20) stearyl ether
  • HY-W440950
    Stearic acid-PEG2000-Mal
    Stearic acid-PEG2000-Mal enables surface modification of various substrate through reaction between hydroxyl and ethoxyl silane. The polymer can be used for click chemistry with alkyne containing molecule.
    Stearic acid-PEG2000-Mal
  • HY-168763
    C23 Phytoceramide
    		99.9%
    C23 Phytoceramide is a long-chain sphingolipid, which is found in C. sinensis.
    C23 Phytoceramide
  • HY-W590679
    113-O16B
    		98.0%
    113-O16B is a disulfide bond-containing ionizable cationic lipidoid. 113-O16B has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA.
    113-O16B
  • HY-134541G
    SM-102 (GMP)
    SM-102 (GMP) is SM-102 (HY-134541) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines.
    SM-102 (GMP)
  • HY-176509C
    DSPE-PEG5000-CHO
    DSPE-PEG5000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG5000-CHO can be used for drug delivery.
    DSPE-PEG5000-CHO