Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1266)
Related Products (1266)
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BAmP-O16B
0 ImagesCat. No.: HY-159725Purity: 98.70%BAmP-O16B is an ionizable cationic amino lipid that can be used to generate lipid nanoparticles (LNPs).
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2H-Cho-Arg TFA
0 Images2H-Cho-Arg (TFA) is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection.
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Dlin-MeOH
0 ImagesDlin-MeOH is an intermediate in the synthesis of DLin-MC3-DMA (HY-112251), which serves as an ionizable lipid component of lipid nanoparticles for mRNA delivery.
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DSPE-PEG2000-CSTSMLKAC
0 ImagesCat. No.: HY-172687DSPE-PEG2000-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). DSPE-PEG2000-CSTSMLKAC can be used for drug delivery DSPE-PEG2000-CSTSMLKAC enables targeted delivery of associated nanoliposomes to ischemic myocardial cells.
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1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol
0 ImagesCat. No.: HY-142991CAS No.: 185435-28-3Synonyms: POPG1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol (POPG) is an anionic phosphatidylglycerol that often serves as a key component to co-construct model phospholipid bilayers with phosphatidylcholine (e.g., at a 3:1 POPC:POPG ratio) for investigating the structure and dynamics of transmembrane proteins. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol acts as a fundamental material for mimicking the physicochemical properties of biological membranes and enables the elucidation of membrane protein interaction mechanisms.
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DSPE-PEG5000-THRPPMWSPVWP
0 ImagesCat. No.: HY-172691DSPE-PEG5000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells.
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4A3-SCC-10
0 ImagesCat. No.: HY-172526CAS No.: 3082361-42-74A3-SCC-10 is a biodegradable ionizable lipid containing disulfide bonds. 4A3-SCC-10 can be used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. 4A3-SCC-10 can be used for broad applications such as gene editing, vaccine, and cancer detection.
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G1-OC2-K3-E10
0 ImagesG1-OC2-K3-E10 is an ionizable lipid, and can be used for delivery of mRNA in lipid nanoparticles (LNPs).
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DSPE-PEG2000-CREKA
0 ImagesCat. No.: HY-172497DSPE-PEG2000-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG2000-CREKA can be used for drug delivery.
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Octadecanedioic acid mono-L-carnitine ester
0 ImagesCat. No.: HY-W800825CAS No.: 123233-50-1Octadecanedioic Acid Mono-L-carnitine ester is a cationic lipid which may be used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Its terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond.
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C14-490
0 ImagesCat. No.: HY-165604CAS No.: 2639634-82-3C14-490 is an ionizable cationic lipid used for the formulation of lipid nanoparticles (LNPs) for mRNA delivery. C14-490 LNPs can be surface-functionalized with CD45 antibodies to enable targeted delivery to hematopoietic stem cells (HSCs), mediate efficient mRNA delivery and CRISPR-Cas9 gene editing in fetal HSCs in utero, with potent and durable genome modulation in HSCs and their progeny. C14-490 is a key component of the Systematically optimized Targeted Editing Machinery (STEM) LNPs for in vivo HSC gene editing applications.
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DSPE-PEG3400-ANG
0 ImagesCat. No.: HY-172699ADSPE-PEG3400-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG3400-ANG can be used for drug delivery.
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DSPE-PEG2000-VHPKQHRGGSKGC
0 ImagesCat. No.: HY-182101ADSPE-PEG2000-VHPKQHRGGSKGC is a targeted modified phospholipid-polyethylene glycol conjugate covalently coupled to DSPE, PEG, and the vascular-targeting peptide VHPKQHRGGSKGC. DSPE-PEG2000-VHPKQHRGGSKGC can be used for research on tumor vascular imaging and vascular-targeted drug delivery.
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1,2-Dihexanoyl-sn-glycero-3-phosphocholine
0 Images1,2-dihexanoyl-sn-glycero-3-phosphocholine is a phosphatidylcholine. It can play a role as a surfactant and is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.
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Amino-Gly-Gly-DSPE hydrochloride
0 ImagesCat. No.: HY-W441005CAS No.: 2446375-49-9Amino-Gly-Gly-DSPE (hydrochloride) is a specially modified phospholipid that has been used to synthesize liposomes. The terminal amine is reactive with an NHS ester compound or carboxylic acid molecule in the presence of activator, such as HATU or EDC.
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Polyoxyethylene (20) stearyl ether
0 ImagesCat. No.: HY-W250183BCAS No.: 9005-00-9Synonyms: Polyethylene glycol octadecyl ether (n～20)Polyoxyethylene (20) stearyl ether (Polyethylene glycol octadecyl ether (n～20)) is a PEGylated lipid surfactant. Polyoxyethylene (20) stearyl ether is used in studies on the formation and stabilization of lipid nanoparticles.
