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Cat. No.: HY-159855

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CAP 2 hydrochloride

(Synonyms: Cholesterol-amino-phosphate 2 hydrochloride)

CAP 2 (Cholesterol-amino-phosphate 2) hydrochloride is Cholesterol-amino-phosphate (CAP) lipid. CAP 2 can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads.

For research use only. We do not sell to patients.

Formula: C₅₉H₁₀₃ClNO₄P
Molecular Weight:956.88

Storage:

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

CAP 2 hydrochloride Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

CAP 2 (Cholesterol-amino-phosphate 2) hydrochloride is Cholesterol-amino-phosphate (CAP) lipid. CAP 2 can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads^[1].

Chemical Information

Appearance Solid
Molecular Weight 956.88
Formula C₅₉H₁₀₃ClNO₄P
Color White to light yellow
SMILES

C[C@]12CC[C@H](OP(O[C@H]3CC[C@]4(C(C3)=CC[C@@]5([C@@]4(CC[C@]6([C@]5(CC[C@@]6([C@H](C)CCCC(C)C)[H])[H])C)[H])[H])C)(OCCCN(C)C)=O)CC1=CC[C@]7([H])[C@]2([H])CC[C@@]8(C)[C@@]7([H])CC[C@@]8([C@H](C)CCCC(C)C)[H].Cl
Synonyms

Cholesterol-amino-phosphate 2 hydrochloride
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Shi Du, et al. Cholesterol-Amino-Phosphate (CAP) Derived Lipid Nanoparticles for Delivery of Self-Amplifying RNA and Restoration of Spermatogenesis in Infertile Mice. Adv Sci (Weinh). 2023 Apr;10(11):e2300188. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
Purity & Documentation
References

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CAP 2 hydrochloride

High-Throughput Bioactive Compound Library

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

CAP 2 hydrochloride Related Classifications

HY-159855 Related Classifications