Protoporphyrinogen IX oxidase Inhibitor

Oxyfluorfen is a pre- and post-emergence diphenyl ether herbicide to control annual broad-leaved and grass weeds. Oxyfluorfen is a protoporphyrinogen oxidase inhibitor and inhibits photosynthesis by blocking chlorophyll synthesis. Oxyfluorfen can inhibit cell growth. Oxyfluorfen induces DNA damage and exhibits toxicity toward aquatic organisms such as Paramisgurnus dabryanus. Oxyfluorfen has genome-level deleterious effects on fish that can lead to stunted skeletal growth. Oxyfluorfen induces transverse limb deficiency or craniosynostosis.

Fomesafen is an orally active herbicide. Fomesafen inhibits protoporphyrinogen oxidase (PPO). Fomesafen induces Apoptosis and increases ROS. Fomesafen exhibits developmental toxicity, immunotoxicity, and neurotoxicity. It induces precancerous lesions in the liver and hepaturoporphyria in mice. Fomesafen is used to control broadleaf weeds in soybean fields, rubber plantations, and orchards.

Saflufenacil is a herbicide of the pyrimidinedione chemical class preplant burndown and selective preemergence dicot weed control in multiple crops, including corn. Saflufenacil is a potent inhibitor of protoporphyrinogen IX oxidase (PPO).

Tiafenacil is a new protoporphyrinogen IX oxidase (PPO)-inhibiting herbicide, with IC₅₀ values of 22 to 28 nM for various plant species, including amaranth (Amaranthus tuberculatus), soybean (Glycine max), arabidopsis (Arabidopsis thaliana), and rapeseed (Brassica napus).

Carfentrazone-ethyl is a selective post-emergence herbicide and protoporphyrinogen oxidase (Protox) inhibitor, with an I₅₀ value of 18 nM against soybean Protox. Carfentrazone-ethyl causes severe damage to target weeds (ivy-leaved morning glory, velvetleaf).

PPO-IN-26 is a Nicotiana tabacum protoporphyrinogen IX oxidase (NtPPO) inhibitor and Herbicide with a NtPPO K_i of 30.3 nM. PPO-IN-26 provides 100% control of 26 tested weed species. PPO-IN-26 shows low injury rates on maize, wheat, and sorghum.

PPO-IN-10 (Compound 4) is a 2-phenylpyridine derivative of pyrrolidone. PPO-IN-10 inhibits protoporphyrinogen IX oxidase (PPO). PPO-IN-10 leads to the formation of photosensitive protoporphyrin IX and the death of weed leaves. PPO-IN-10 can be used in the research of developing new PPO herbicides.

Bifenox-d₃ is the deuterium labeled Bifenox. Bifenox (MC-4379) is a nitrophenyl ether herbicide. Bifenox disrupts cellular membrane, inhibits photosynthesis and inhibits the protoporphyrinogen oxidase. Bifenox increases the ROS production in the microalgae Chlamydomonas reinhardtii.

PPO-IN-2 is an inhibitor of protoporphyrinogen IX oxidase with an K_i of 16 nM.

PPO-IN-3 (Compound 8ad) is a PPO inhibitor with an K_I value of 0.67 nM. PPO-IN-3 has post-emergence herbicidal activity. PPO-IN-3 can be used for weed control.

PPO-IN-14 (compound B11) is a Nicotiana tobacco Protoporphyrinogen oxidase (NtPPO) inhibitor, with a K_i value of 9.05 nM. PPO-IN-14 (compound B11) could help control weeds in agricultural production.

Saflufenacil (Standard) is the analytical standard of Saflufenacil. This product is intended for research and analytical applications. Saflufenacil is a herbicide of the pyrimidinedione chemical class preplant burndown and selective preemergence dicot weed control in multiple crops, including corn. Saflufenacil is a potent inhibitor of protoporphyrinogen IX oxidase (PPO).

PPO-IN-11 (Compound 10bh) is an inhibitor for protoporphyrinogen IX oxidase (PPO), that inhibits nicotiana tabacum PPO (NtPPO) with K_i of 0.0603 μM. PPO-IN-11 exhibits herbicidal activities against dicot weeds Leaf mustard, Chickweed, Chenopodium serotinum and monocot weeds Alopecurus aequalis, Poa annua, and Polypogon fugax with a dose of 150 g a.i./ha.

PPO-IN-20 (Compound B18) is a Protoporphyrinogen IX oxidase (PPO, protoporphyrinogen IX oxidase) inhibitor, with a K_i value of 10.3 nM for NtPPO. PPO-IN-20 shows broad-spectrum herbicidal activity and can be used for research in the agricultural field.

Fomesafen-d₃ is the deuterium-labeled Fomesafen (HY-B2010). Fomesafen is an orally active herbicide. Fomesafen inhibits protoporphyrinogen oxidase (PPO). Fomesafen induces Apoptosis and increases ROS. Fomesafen exhibits developmental toxicity, immunotoxicity, and neurotoxicity. It induces precancerous lesions in the liver and hepaturoporphyria in mice. Fomesafen is used to control broadleaf weeds in soybean fields, rubber plantations, and orchards.

PPO-IN-17 (Compound 6R) is the inhibitor protoporphyrinogen IX oxidase (PPO) that inhibits Nicotiana tobacco PPO (NtPPO) with K_i of 30.34 nM. PPO-IN-17 exhibits herbicidal activity that inhibits barnyardgrass (E. crus-galli), foxtail grass (D. sanguinalis), alfalfa (M. sativa) and Canada cocklebur (C. canadensis) (>95% inhibition rate at a concentration of 37.5 g/hm²). PPO-IN-17 exhibits no toxicity on rice (at a concentration of 75 g/hm²) or on honeybees (at a concentration of 6400 mg/kg).