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Tiafenacil 

Cat. No.: HY-137551
Handling Instructions

Tiafenacil is a new protoporphyrinogen IX oxidase (PPO)-inhibiting herbicide, with IC50 values of 22 to 28 nM for various plant species, including amaranth (Amaranthus tuberculatus), soybean (Glycine max), arabidopsis (Arabidopsis thaliana), and rapeseed (Brassica napus).

For research use only. We do not sell to patients.

Tiafenacil Chemical Structure

Tiafenacil Chemical Structure

CAS No. : 1220411-29-9

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Description

Tiafenacil is a new protoporphyrinogen IX oxidase (PPO)-inhibiting herbicide, with IC50 values of 22 to 28 nM for various plant species, including amaranth (Amaranthus tuberculatus), soybean (Glycine max), arabidopsis (Arabidopsis thaliana), and rapeseed (Brassica napus)[1].

In Vitro

Tiafenacil has low oral and dermal acute toxicity[1].
In velvetleaf, Tiafenacil causes severe growth inhibition at 1 µM and results in desiccation and death at 5 µM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

511.87

Formula

C₁₉H₁₈ClF₄N₃O₅S

CAS No.

1220411-29-9

SMILES

FC(C(N(C(C=C1C(F)(F)F)=O)C(N1C)=O)=C2)=CC(Cl)=C2SC(C)C(NCCC(OC)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (195.36 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9536 mL 9.7681 mL 19.5362 mL
5 mM 0.3907 mL 1.9536 mL 3.9072 mL
10 mM 0.1954 mL 0.9768 mL 1.9536 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (4.88 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: 2.5 mg/mL (4.88 mM); Suspended solution; Need ultrasonic

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (4.88 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

TiafenacilOthersInhibitorinhibitorinhibit

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Tiafenacil
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