2. Signaling Pathways
  3. Neuronal Signaling
  4. Tau Protein
  5. Tau Protein p53 Inhibitor

Tau Protein p53 Inhibitor

Tau Protein p53 Inhibitor (1):

Cat. No. Product Name Effect Purity
  • HY-W143216
    Azure C
    		p53 Inhibitor
    Azure C (Monomethylthionine) acts as a tau oligomer inhibitor and Aβ42 oligomerization inhibitor. Azure C regulates hsp70 ATPase activity, thereby mediating the clearance of tau protein. Azure C reduces the levels of toxic tau oligomers by promoting the formation of non-toxic tau aggregates, rescues neuroblastoma cells from tau oligomer-induced toxicity, and binds to and inhibits Aβ42 oligomerization. Azure C is generated via continuous oxidation of methylene blue or azure B through a horseradish peroxidase-mediated reaction. Azure C can be used in research related to tauopathies, including Alzheimer's disease.