2. Antibody-Drug Conjugate/ADC Related
  3. ADC Linkers
  4. Alkyne-PEG5-SNAP

Alkyne-PEG5-SNAP  (Synonyms: Alkyne-PEG5-BG)

Cat. No.: HY-151646 Pureza: 98.95%
COA
SDS
Instrucciones de manejo Technical Support

Alkyne-PEG5-SNAP is a click chemistry reagent containing an alkyne group. Alkyne-PEG5-SNAP can alkyne conjugated benzylguanine (BG), the BG moiety reacts specifically and rapidly with SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation. Alkyne-PEG5-SNAP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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Alkyne-PEG5-SNAP

Alkyne-PEG5-SNAP Estructura química

Tamaño Precio Stock Cantidad
Muestra gratis (0.1 - 0.2 mg)   Solicite ahora  
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
5 mg En stock
10 mg En stock
25 mg En stock
50 mg   Obtener un presupuesto  
100 mg   Obtener un presupuesto  

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Alkyne-PEG5-SNAP Related Antibodies

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Descripciòn

Alkyne-PEG5-SNAP is a click chemistry reagent containing an alkyne group. Alkyne-PEG5-SNAP can alkyne conjugated benzylguanine (BG), the BG moiety reacts specifically and rapidly with SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation[1]. Alkyne-PEG5-SNAP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Peso molecular

556.61

Fòrmula

C27H36N6O7
Appearance

Solid

Color

White to off-white

SMILES

O=C(NCC1=CC=C(COC2=C3N=CNC3=NC(N)=N2)C=C1)CCOCCOCCOCCOCCOCC#C
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

DMSO : 125 mg/mL (224.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7966 mL 8.9830 mL 17.9659 mL
5 mM 0.3593 mL 1.7966 mL 3.5932 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7966 mL 8.9830 mL 17.9659 mL 44.9148 mL
5 mM 0.3593 mL 1.7966 mL 3.5932 mL 8.9830 mL
10 mM 0.1797 mL 0.8983 mL 1.7966 mL 4.4915 mL
15 mM 0.1198 mL 0.5989 mL 1.1977 mL 2.9943 mL
20 mM 0.0898 mL 0.4491 mL 0.8983 mL 2.2457 mL
25 mM 0.0719 mL 0.3593 mL 0.7186 mL 1.7966 mL
30 mM 0.0599 mL 0.2994 mL 0.5989 mL 1.4972 mL
40 mM 0.0449 mL 0.2246 mL 0.4491 mL 1.1229 mL
50 mM 0.0359 mL 0.1797 mL 0.3593 mL 0.8983 mL
60 mM 0.0299 mL 0.1497 mL 0.2994 mL 0.7486 mL
80 mM 0.0225 mL 0.1123 mL 0.2246 mL 0.5614 mL
100 mM 0.0180 mL 0.0898 mL 0.1797 mL 0.4491 mL
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Alkyne-PEG5-SNAP Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Alkyne-PEG5-SNAPAlkyne-PEG5-BGADC LinkersAntibody-drug conjugates linkersclick chemistry reagentalkynebenzylguanineSNAP-tagconjugationInhibitorinhibitorinhibit

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Nombre del producto:
Alkyne-PEG5-SNAP
Cat. No.:
HY-151646
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