Amaralin 

Amaralin is a sesquiterpene lactone with analgesic activity, which exists in the leaves and stems of Helenium amarum (Raf.) H. Rock. When administered subcutaneously, Amaralin produces analgesic effects in the mouse tail-flick test. When administered subcutaneously, Amaralin inhibits acetic acid-induced writhing syndrome in mice. Amaralin can be used for pain-related research^[1].

Amaralin (compound Ia) is a pseudoguaianolide sesquiterpene lactone. It readily forms monoacetate at room temperature^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Amaralin (compound Ia) (10-25 mg/kg; s.c.) produces potent analgesic effects in mouse tail flick test and inhibits acetic acid-induced writhing syndrome in mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

264.32

C₁₅H₂₀O₄

6831-10-3

C[C@]12[C@@]([C@@]3([C@]([C@@H]1O)(O3)[H])[H])([C@H](C)C[C@]4([C@](C2)(C(=C)C(=O)O4)[H])[H])[H]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Lucas R A, et al. A New Sesquiterpene Lactone with Analgesic Activity from Helenium amarum (Raf.) H. Rock. The Journal of Organic Chemistry, 1964, 29(6): 1549-1554.