Amino-PEG3-C2-sulfonic acid
Based on 1 Customer Validation
Amino-PEG3-C2-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.47%
- CAS No.: 1817735-43-5
- Formula: C8H19NO6S
- Molecular Weight:257.30
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
All PROTAC Linkers Isoforms
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Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1817735-43-5
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Appearance Oil
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Molecular Weight 257.30
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Formula C8H19NO6S
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Color Colorless to light yellow
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SMILES
NCCOCCOCCOCCS(=O)(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (388.65 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8865 mL | 19.4326 mL | 38.8651 mL | 97.1628 mL |
| 5 mM | 0.7773 mL | 3.8865 mL | 7.7730 mL | 19.4326 mL | |
| 10 mM | 0.3887 mL | 1.9433 mL | 3.8865 mL | 9.7163 mL | |
| 15 mM | 0.2591 mL | 1.2955 mL | 2.5910 mL | 6.4775 mL | |
| 20 mM | 0.1943 mL | 0.9716 mL | 1.9433 mL | 4.8581 mL | |
| 25 mM | 0.1555 mL | 0.7773 mL | 1.5546 mL | 3.8865 mL | |
| 30 mM | 0.1296 mL | 0.6478 mL | 1.2955 mL | 3.2388 mL | |
| 40 mM | 0.0972 mL | 0.4858 mL | 0.9716 mL | 2.4291 mL | |
| 50 mM | 0.0777 mL | 0.3887 mL | 0.7773 mL | 1.9433 mL | |
| 60 mM | 0.0648 mL | 0.3239 mL | 0.6478 mL | 1.6194 mL | |
| 80 mM | 0.0486 mL | 0.2429 mL | 0.4858 mL | 1.2145 mL | |
| 100 mM | 0.0389 mL | 0.1943 mL | 0.3887 mL | 0.9716 mL |