Amino-PEG7-C2-SH hydrochloride
Based on 1 Customer Validation
Amino-PEG7-C2-SH hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.0%
- Formula: C16H36ClNO7S
- Molecular Weight:421.98
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All PROTAC Linkers Isoforms
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Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Liquid
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Molecular Weight 421.98
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Formula C16H36ClNO7S
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Color Light yellow to yellow
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SMILES
SCCOCCOCCOCCOCCOCCOCCOCCN.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : ≥ 250 mg/mL (592.45 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3698 mL | 11.8489 mL | 23.6978 mL | 59.2445 mL |
| 5 mM | 0.4740 mL | 2.3698 mL | 4.7396 mL | 11.8489 mL | |
| 10 mM | 0.2370 mL | 1.1849 mL | 2.3698 mL | 5.9245 mL | |
| 15 mM | 0.1580 mL | 0.7899 mL | 1.5799 mL | 3.9496 mL | |
| 20 mM | 0.1185 mL | 0.5924 mL | 1.1849 mL | 2.9622 mL | |
| 25 mM | 0.0948 mL | 0.4740 mL | 0.9479 mL | 2.3698 mL | |
| 30 mM | 0.0790 mL | 0.3950 mL | 0.7899 mL | 1.9748 mL | |
| 40 mM | 0.0592 mL | 0.2962 mL | 0.5924 mL | 1.4811 mL | |
| 50 mM | 0.0474 mL | 0.2370 mL | 0.4740 mL | 1.1849 mL | |
| 60 mM | 0.0395 mL | 0.1975 mL | 0.3950 mL | 0.9874 mL | |
| 80 mM | 0.0296 mL | 0.1481 mL | 0.2962 mL | 0.7406 mL | |
| 100 mM | 0.0237 mL | 0.1185 mL | 0.2370 mL | 0.5924 mL |