2. Metabolic Enzyme/Protease
  3. Carbonic Anhydrase
  4. Aminozolamide

Aminozolamide is a carbonic anhydrase inhibitor. Aminozolamide regulates intraocular pressure by inhibiting carbonic anhydrase activity. Aminozolamide exerts local ocular effects, exhibits good retention in the ciliary body of rabbit eyes, and prevents rapid elimination from the eye. Aminozolamide is applicable to the research of ocular hypertension.

For research use only. We do not sell to patients.

Aminozolamide

Aminozolamide Chemical Structure

CAS No. : 94641-11-9

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Aminozolamide Related Antibodies

Top Publications Citing Use of Products

View All Carbonic Anhydrase Isoform Specific Products:

View All Isoforms
CA CA I CA Ⅱ CA IX CA XII CA VII CA VI CA VA CA VB CA XIII CA XIV

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Aminozolamide is a carbonic anhydrase inhibitor. Aminozolamide regulates intraocular pressure by inhibiting carbonic anhydrase activity. Aminozolamide exerts local ocular effects, exhibits good retention in the ciliary body of rabbit eyes, and prevents rapid elimination from the eye. Aminozolamide is applicable to the research of ocular hypertension[1].

In Vivo

Aminozolamide (3%; topical ocular administration; single 50 μL instillation to one eye) reduces intraocular pressure in normotensive rabbits. Its metabolites exhibit equivalent potency, so this compound can persist in the eye to support long-term inhibition of carbonic anhydrase[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: normotensive rabbits[1]
Dosage: 3%
Administration: topical ocular; single 50 μL instillation (to one eye)
Result: Lowered IOP in normotensive rabbits, with potency equivalent to other ethoxzolamide analog gels tested.
Was well retained within the rabbit ciliary body, along with its 6-acetamido-2-benzothiazolesulfonamide metabolite, preventing rapid ocular removal and enabling sustained carbonic anhydrase inhibition.
Molecular Weight

229.27

Formula

C7H7N3O2S2
CAS No.
SMILES

O=S(=O)(N)C1=NC=2C=CC(N)=CC2S1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Aminozolamide Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aminozolamide94641-11-9Carbonic AnhydraseCarbonate dehydrataseciliary bodyocular hypertensioncarbonic anhydrase6-acetamido-2-benzothiazolesulfonamidenormotensive rabbitsintraocular pressureethoxzolamide analog gelsrabbit eyeInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Aminozolamide
Cat. No.:
HY-W566406
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.