ACD Antibody (YA8057)

Cat. No.: HY-P88373: Data Sheet User Guide for Antibodies
FAQs
Technical Support

ACD Antibody (YA8057) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ACD.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

* Please select Quantity before adding items.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

ACD Antibody (YA8057) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ACD.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 57.6 kDa

Species Reactivity

Human

SwissProt ID

Q96AP0

Immunogen

Full length human recombinant protein of human ACD produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis

Subcellular Localization：Nucleus,Chromosome, telomere

Isoforms & Post-Translational Modification：Q96AP0 has two isomers: Q96AP0-3: 48967 Da (predicted); Q96AP0-2: 48627 Da (predicted).

Subunit：Component of the shelterin complex (telosome) composed of TERF1, TERF2, TINF2, TERF2IP ACD and POT1

Synonyms

PIP1; PTOP; TINT1; TPP1

Documentation

User Guide for Antibodies (1077 KB)