AIF Antibody (YA835)

Cat. No.: HY-P80534: FAQs
Data Sheet SDS COA User Guide for Antibodies

AIF Antibody (YA835) is a non-conjugated and Mouse origined monoclonal antibody about 67 kDa, targeting to AIF (8H1). It can be used for WB,ICC/IF assays with tag free, in the background of Human.

For research use only. We do not sell to patients.

Size	Price	Stock	Quantity
10 μL	$70	In-stock	Estimated Time of Arrival: December 31
50 μL	$185	In-stock	Estimated Time of Arrival: December 31
100 μL	$300	In-stock	Estimated Time of Arrival: December 31
250 μL		Get quote

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Biological Activity
Technical Parameters
Properties
Documentation

Description	AIF Antibody (YA835) is a non-conjugated and Mouse origined monoclonal antibody about 67 kDa, targeting to AIF (8H1). It can be used for WB,ICC/IF assays with tag free, in the background of Human.
Background	AIF (8H1): This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and cognitive disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, Aug 2015]
Tag	Free
Gene ID	9131
Synonyms	AIFM1; AIF; PDCD8; Apoptosis-inducing factor 1; mitochondrial; Programmed cell death protein 8
Molecular Weight	Predicted band size: 67 kDa
Purity	affinity purified
Conjugation	Non-conjugated
Research Field	Cell Biology
Product Categories	Primary Antibody; Mouse Monoclonal Antibody
Host	Mouse
Reactivity	Human
SwissProt ID	O95831
Dilution Ratio	WB: 1:500-1:1,000 ;IF: 1:50-1:200
Application	WB, ICC/IF
Appearance	Liquid
Formulation	Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG2a
Immunogen	Synthetic peptide corresponding to Human AIF.The exact sequence is proprietary to MCE.
Documentation	Select Batch: Data Sheet (235 KB) SDS (251 KB) COA (205 KB) User Guide for Antibodies (1077 KB)

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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AIF Antibody (YA835)

Biological Activity

Technical Parameters

Properties

Documentation

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