alpha Sarcoglycan Antibody (YA2068)(PBS only)

Cat. No.: HY-P82323A: Data Sheet User Guide for Antibodies
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alpha Sarcoglycan Antibody (YA2068) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to alpha Sarcoglycan.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

alpha Sarcoglycan Antibody (YA2068) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to alpha Sarcoglycan.

Host

Rabbit

Molecular Weight

Predicted band size: 43 kDa;

Observed band size: 50 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q16586

Gene ID

6442 [NCBI]

Immunogen

A synthetic peptide of human alpha Sarcoglycan

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
IP IP: Immunoprecipitation	1:20

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix

Subcellular Localization：Cell membrane, sarcolemma; Single-pass type I membrane protein; Cytoplasm, cytoskeleton

Expression：
Tissue_specificity:Most strongly expressed in skeletal muscle. Also expressed in cardiac muscle and, at much lower levels, in lung. In the fetus, most abundant in cardiac muscle and, at lower levels, in lung. Also detected in liver and kidney. Not expressed in brain

Isoforms & Post-Translational Modification：Q16586 has 2 isomers: Q16586-1: 42875 Da (predicted); Q16586-2: 29354 Da (predicted).

Subunit：Interacts with the syntrophin SNTA1. Cross-link to form 2 major subcomplexes: one consisting of SGCB, SGCD and SGCG and the other consisting of SGCB and SGCD.

Research Field

Signal Transduction

Synonyms

SGCA; ADL; DAG2; Alpha-sarcoglycan; Alpha-SG; 50 kDa dystrophin-associated glycoprotein; 50DAG; Adhalin; Dystroglycan-2

Documentation

User Guide for Antibodies (1077 KB)