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Cat. No.: HY-P87766

AMPKβ1 Antibody (YA7451)

AMPKβ1 Antibody (YA7451) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to AMPKβ1.

For research use only. We do not sell to patients.

Formulation:
Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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Stock

Quantity

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	IHC-P IHC-P: Immunohistochemistry-Paraffin	WB WB: Western Blot	ICC/IF ICC/IF: Immunocytochemistry/ Immunofluorescence	ELISA ELISA: Enzyme Linked Immunosorbent Assay	IP IP: Immunoprecipitation
Dilution Ratio	1:100-1:500	1:2000-1:10000	1:200-1:1000	1:5000-1:20000	1:50-1:200

Description

AMPKβ1 Antibody (YA7451) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to AMPKβ1.

Host Rabbit
Clonality Monoclonal,Recombinant
Species Reactivity
Human, Mouse, Rat
Observed Molecular Weight

Observed band size: 38 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 30 kDa

Immunogen

The exact sequence is proprietary to MCE.

Sensitivity

Endogenous

Purification

Protein A affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG,Kappa

Appearance

Liquid
Formulation

Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

AMPKβ1 is a Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3)
Isoforms & Post-Translational Modification

Q9Y478: 270 amino acids, molecular weight 30382 Da.
Subunit

AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or PRKAG3)
SwissProt ID

Q9Y478