Axin 2 Antibody (YA7253)
Axin 2 Antibody (YA7253) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Axin 2.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, ICC/IF
-
Reactivity :
Human, Mouse, Rat
-
Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:50-200 |
Product Details
Axin 2 Antibody (YA7253) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Axin 2.
-
Host Rabbit
-
Clonality Recombinant,Monoclonal
-
Species ReactivityHuman, Mouse, Rat
-
Observed Molecular WeightObserved band size: 94 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 94 kDa
A synthesized peptide derived from human Axin 2
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
Axin 2 is an Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B
-
Subcellular Localization
Cytoplasm
-
Expression
Tissue_Specificity: Expressed in brain and lymphoblast -
Isoforms & Post-Translational Modification
Q9Y2T1: 843 amino acids, molecular weight 93568 Da.
-
Subunit
Interacts with glycogen synthase kinase-3 beta (GSK3B) and beta-catenin
-
SwissProt ID
Documentation
Powered by Bioz
