Baf180 Antibody (YA1176)(PBS only)

Cat. No.: HY-P81431A: Data Sheet User Guide for Antibodies
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Baf180 Antibody (YA1176) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Baf180.

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사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

Baf180 Antibody (YA1176) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Baf180.

Host

Rabbit

분자량

Predicted band size: 193 kDa;

Observed band size: 193 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q86U86

Gene ID

55193 [NCBI]

Immunogen

Recombinant protein of human Baf180

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-1:200

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation

Subcellular Localization：Nucleus

Expression：
Tissue_specificity:Widely expressed

Isoforms & Post-Translational Modification：Q86U86 has 9 isomers: Q86U86-1: 192948 Da (predicted); Q86U86-2: 187188 Da (predicted); Q86U86-3: 183690 Da (predicted); Q86U86-4: 181085 Da (predicted); Q86U86-5: 182118 Da (predicted); Q86U86-6: 99142 Da (predicted); Q86U86-7: 183885 Da (predicted); Q86U86-8: 189645 Da (predicted); Q86U86-9: 184043 Da (predicted).

Subunit：Component of the SWI/SNF-B (PBAF) chromatin remodeling complex, at least composed of SMARCA4/BRG1, SMARCB1/BAF47/SNF5, ACTL6A/BAF53A or ACTL6B/BAF53B, SMARCE1/BAF57, SMARCD1/BAF60A, SMARCD2/BAF60B, perhaps SMARCD3/BAF60C, SMARCC1/BAF155, SMARCC2/BAF170, PBRM1/BAF180, ARID2/BAF200 and actin. Interacts with PHF10/BAF45A (By similarity). Interacts with acetylated 'Lys-14' of histone H3 (H3K14ac), and may also interact with other acetylated or methylated Lys residues on histone H3

Research Field

Epigenetics and Nuclear Signaling

Synonyms

BAF180; hPB1; PB1; Pbrm1; polybromo 1; Polybromo-1D

각종 서류

User Guide for Antibodies (1077 KB)