BMPR1A Antibody
(Synonyms: ALK3; SKR5; CD292; ACVRLK3; 10q23del)BMPR1A Antibody is a rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to BMPR1A.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, IHC-P, IHC-F, IF-Tissue
-
Reactivity :
Human, Rat
-
Formulation:
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
IHC-F
IHC-F: Immunohistochemistry-Frozen
|
IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
|
|---|---|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:100-500 | 1:100-500 | 1:100-500 |
Product Details
BMPR1A Antibody is a rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to BMPR1A.
-
Host Rabbit
-
Clonality Polyclonal
-
Species ReactivityHuman, Rat Predicted Reactivity: Mouse
Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
-
Observed Molecular WeightObserved band size: 60 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 60 kDa
KLH conjugated synthetic peptide derived from human BMPR-1A : 101-200/532
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
BMPR1A is an On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6. May promote the expression of HAMP, potentially via its interaction with BMP2
-
Subcellular Localization
Cell membrane,Cell surface
-
Expression
Tissue_Specificity: Highly expressed in skeletal muscle -
Isoforms & Post-Translational Modification
P36894: 532 amino acids, molecular weight 60198 Da.
-
Subunit
Interacts with low affinity with GDF5; positively regulates chondrocyte differentiation (PubMed:24098149)
-
SwissProt ID
-
Synonyms
ALK3; SKR5; CD292; ACVRLK3; 10q23del
Documentation
Powered by Bioz
