BRP44L Antibody
(Synonyms: BRP44L, CGI-129, HSPC040, PNAS-115, MPC1, Mitochondrial pyruvate carrier 1, Brain protein 44-like protein)
Based on 1 Customer Validation
BRP44L Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to BRP44L.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat, Monkey, Bovine
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:500-1000 | 1:100-200 | 1:100-500 |
Product Details
BRP44L Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to BRP44L.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat, Monkey, Bovine
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Observed Molecular WeightObserved band size: 12 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 12 kDa
Synthetic peptide corresponding to the N-term region of human BRP44L.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
BRP44L mediates the uptake of pyruvate into mitochondria to maintain the balance between glycolysis and oxidative phosphorylation. Plays an essential role in cellular metabolism[1][2][3][4][5].
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Subcellular Localization
Mitochondrion inner membrane
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Isoforms & Post-Translational Modification
BRP44L has an amino acid length of 109, molecular weight is 12347 Da.
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Subunit
Heterodimer; dimerises with MPC2 to form a functional mitochondrial pyruvate carrier.
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SwissProt ID
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Synonyms
BRP44L, CGI-129, HSPC040, PNAS-115, MPC1, Mitochondrial pyruvate carrier 1, Brain protein 44-like protein
Documentation
[1]. Bricker DK, et al. A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans. Science. 2012 Jul 6;337(6090):96-100. [Content Brief]
[2]. Compan V, et al. Monitoring Mitochondrial Pyruvate Carrier Activity in Real Time Using a BRET-Based Biosensor: Investigation of the Warburg Effect. Mol Cell. 2015 Aug 6;59(3):491-501. [Content Brief]
[3]. Vanderperre B, et al. MPC1-like Is a Placental Mammal-specific Mitochondrial Pyruvate Carrier Subunit Expressed in Postmeiotic Male Germ Cells. J Biol Chem. 2016 Aug 5;291(32):16448-61. [Content Brief]
[4]. He Z, et al. Structure of mitochondrial pyruvate carrier and its inhibition mechanism. Nature. 2025 May;641(8061):250-257. [Content Brief]
[5]. Liang J, et al. Structures and mechanism of the human mitochondrial pyruvate carrier. Nature. 2025 May;641(8061):258-265. [Content Brief]
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