C4 Binding Protein Antibody (YA1873)
(Synonyms: C4BP; C4BPB; PRP)C4 Binding Protein Antibody (YA1873) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to C4 Binding Protein.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, IHC-P, ICC/IF, IP
-
Reactivity :
Human, Rat
-
Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IP
IP: Immunoprecipitation
|
|---|---|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:100 | 1:50-1:200 | 1:60 |
Product Details
C4 Binding Protein Antibody (YA1873) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to C4 Binding Protein.
-
Host Rabbit
-
Clonality Recombinant, Monoclonal
-
Species ReactivityHuman, Rat
-
Observed Molecular WeightObserved band size: 45 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 28 kDa
A synthesized peptide derived from human C4 binding protein aa1-252/252.
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
C4 Binding Protein controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S
-
Subcellular Localization
Secreted
-
Isoforms & Post-Translational Modification
P20851 has 2 isomers: P20851-1: 28357 Da (predicted); P20851-2: 28286 Da (predicted).
-
Subunit
Disulfide-linked complex of alpha and beta chains of 3 possible sorts: a 570 kDa complex of 7 alpha chains and 1 beta chain, a 530 kDa homoheptamer of alpha chains or a 500 kDa complex of 6 alpha chains and 1 beta chain. The central body of the alpha chain homomer supports tentacles, each with the binding site for C4b at the end
-
SwissProt ID
-
Synonyms
C4BP; C4BPB; PRP
-
Research Field
Immunology
Documentation
Powered by Bioz
