CAPN1 Antibody (YA7201)
(Synonyms: CANPL1, PIG30, CAPN1, Calpain-1 catalytic subunit, Calcium-activated neutral proteinase 1, Calpain mu-type, Calpain-1 large subunit, Cell proliferation-inducing gene 30 protein, Micromolar-calpain, CANP 1, muCANP)
Based on 1 Customer Validation
CAPN1 Antibody (YA7201) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CAPN1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
ICC/IF
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Reactivity :
Human
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Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|
| Dilution Ratio | 1:50-200 |
Product Details
CAPN1 Antibody (YA7201) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CAPN1.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman Predicted Reactivity: Mouse,Rat
Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
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Observed Molecular WeightObserved band size: 75,80 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 82 kDa
A synthesized peptide derived from human Calpain 1 catalytic subunit: 154-200.
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CAPN1 is a Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His-409'. Cleaves and activates caspase-7 (CASP7)[1][2][3][4].
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Subcellular Localization
Cytoplasm,Cell membrane
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Expression
Tissue_Specificity: Ubiquitous -
Isoforms & Post-Translational Modification
P07384: 714 amino acids, molecular weight 81890 Da.
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Subunit
Forms a heterodimer with a small (regulatory) subunit CAPNS1
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SwissProt ID
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Synonyms
CANPL1, PIG30, CAPN1, Calpain-1 catalytic subunit, Calcium-activated neutral proteinase 1, Calpain mu-type, Calpain-1 large subunit, Cell proliferation-inducing gene 30 protein, Micromolar-calpain, CANP 1, muCANP
Documentation
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