2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. CCL23 Antibody (YA2929)

CCL23 Antibody (YA2929) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CCL23.

For research use only. We do not sell to patients.

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

  • References

Description

CCL23 Antibody (YA2929) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CCL23.
Host

Rabbit
Clonality

Recombinant,Monoclonal
Molecular Weight
Predicted band size: 13 kDa;
Observed band size: 13 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from human CCL23 aa1-60/120.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:1000-1:2000
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:50-1:200
Sensitivity Endogenous Purity Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in rabbit IgG in 10 mM PBS, pH 7.4, 150 mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than CCL23
Subcellular Localization：Secreted
Expression：
Tissue_specificity:High levels in human lung, liver, skeletal muscle and pancreas. Moderate levels in fetal liver, human bone marrow and placenta. The short form is the major species and the longer form was detected only in very low abundance. CCL23 (19-99) , CCL23 (22-99) , CCL23 (27-99) , CCL23 (30-99) are found in high levels in synovial fluids from rheumatoid.
Isoforms & Post-Translational Modification：P55773 has 2 isomers: P55773-1: 13443 Da (predicted); P55773-2: 15322 Da (predicted).
The N-terminal is proteolytically cleaved by proteases associated with inflammatory responses. The processed forms, CCL23(19-99), CCL23(22-99), CCL23(27-99) and CCL23(30-99) exhibit increase in CCR1-mediated signaling and chemotaxis assays in vitro
Database

Entrez Gene: 6368 Human

SwissProt: P55773 Human

OMIM: 602494 Human

Research Field

Immunology
Synonyms
CCL23; CKB8; Hmrp-2a; MIP3; MPIF1; SCYA23
Documentation
SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)
References

CCL23 Antibody (YA2929) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
CCL23 Antibody (YA2929)
Cat. No.:
HY-P83184
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