CCL23 Antibody (YA2929)
(Synonyms: CCL23; CKB8; Hmrp-2a; MIP3; MPIF1; SCYA23)
Based on 1 Customer Validation
CCL23 Antibody (YA2929) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CCL23.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, ICC/IF
-
Reactivity :
Human
-
Formulation:
Supplied in rabbit IgG in 10 mM PBS, pH 7.4, 150 mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:1000-1:2000 | 1:50-1:200 |
Product Details
CCL23 Antibody (YA2929) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CCL23.
-
Host Rabbit
-
Clonality Recombinant,Monoclonal
-
Species ReactivityHuman
-
Observed Molecular WeightObserved band size: 13 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 13 kDa
A synthesized peptide derived from human CCL23 aa1-60/120.
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in rabbit IgG in 10 mM PBS, pH 7.4, 150 mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
-
Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
CCL23 is a Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than CCL23
-
Subcellular Localization
Secreted
-
Expression
Tissue_specificity:High levels in human lung, liver, skeletal muscle and pancreas. Moderate levels in fetal liver, human bone marrow and placenta. The short form is the major species and the longer form was detected only in very low abundance. CCL23 (19-99) , CCL23 (22-99) , CCL23 (27-99) , CCL23 (30-99) are found in high levels in synovial fluids from rheumatoid. -
Isoforms & Post-Translational Modification
P55773 has 2 isomers: P55773-1: 13443 Da (predicted); P55773-2: 15322 Da (predicted).
The N-terminal is proteolytically cleaved by proteases associated with inflammatory responses. The processed forms, CCL23(19-99), CCL23(22-99), CCL23(27-99) and CCL23(30-99) exhibit increase in CCR1-mediated signaling and chemotaxis assays in vitro -
SwissProt ID
-
Synonyms
CCL23; CKB8; Hmrp-2a; MIP3; MPIF1; SCYA23
-
Research Field
Immunology
Documentation
Powered by Bioz
