CD161 Antibody (YA4661)
(Synonyms: KLRB1; CLEC5B; NKRP1A; Killer cell lectin-like receptor subfamily B member 1; C-type lectin domain family 5 member B; HNKR-P1a; NKR-P1A; Natural killer cell surface protein P1A; CD161)CD161 Antibody (YA4661) is a non-conjugated antibody, targeting to CD161.
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Formulation:
Supplied in Phosphate-buffered solution.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Product Details
CD161 Antibody (YA4661) is a non-conjugated antibody, targeting to CD161.
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Clonality Monoclonal
affinity purified.
Non-conjugated
Unmodified
Product Properties
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Appearance
Solution
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Formulation
Supplied in Phosphate-buffered solution.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD161 (KLRB1/NKR-P1A) is a C-type lectin-like immune receptor primarily expressed on NK cells, NKT cells, MAIT cells, and a subset of Th17 cells; it serves as an important marker for studying the crosstalk between innate and adaptive immunity.
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Subcellular Localization
Membrane; Single-pass type II membrane protein
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Expression
Tissue_specificity:It is primarily expressed in NK cell subsets in the intestinal epithelium and liver. It can be detected in peripheral blood T cells, especially in adult T cells with a memory antigen phenotype.
Induction:By IL12/interleukin-12 in NK cells -
Subunit
Homodimer; disulfide-linked. Interacts with acid sphingomyelinase/SMPD1
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SwissProt ID
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Synonyms
KLRB1; CLEC5B; NKRP1A; Killer cell lectin-like receptor subfamily B member 1; C-type lectin domain family 5 member B; HNKR-P1a; NKR-P1A; Natural killer cell surface protein P1A; CD161
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