TACI Antibody (YA3512)

Cat. No.: HY-P83815: Ficha de datos User Guide for Antibodies
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TACI Antibody (YA3512) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TACI.

Para uso exclusivo en investigación. No vendemos a pacientes.

Tamaño	Stock	Cantidad
20 μL	Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn

Descripciòn

TACI Antibody (YA3512) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TACI.

Host

Mouse

Clonality

Monoclonal Antibody

Peso molecular

Predicted band size: 31.8 kDa;

Observed band size: 32 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

O14836

Gene ID

23495 [NCBI]

Immunogen

Purified recombinant fragment of human CD267 (AA: extra(1-165)) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Pureza	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS with 0.05% sodium azide

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity

Subcellular Localization：Membrane; Single-pass type III membrane protein

Expression：
Tissue_specificity:It is highly expressed in the spleen, thymus, small intestine, and peripheral blood leukocytes. It is expressed in resting B cells and activated T cells, but not in resting T cells.

Isoforms & Post-Translational Modification：O14836 has 3 isomers: O14836-1: 31816 Da (predicted); O14836-2: 26664 Da (predicted); O14836-3: 19865 Da (predicted).

Subunit：Binds TRAF2, TRAF5 and TRAF6. Binds the NH2-terminal domain of CAMLG with its C-terminus

Synonyms

CVID; RYZN; TACI; CD267; CVID2; IGAD2; TNFRSF14B

Documentación

User Guide for Antibodies (1077 KB)