CD57 Antibody (YA4691)
(Synonyms: B3GAT1; GLCATP; Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1; Beta-1; 3-glucuronyltransferase 1; Glucuronosyltransferase P; GlcAT-P; UDP-GlcUA:glycoprotein beta-1; 3-glucuronyltransferase; GlcUAT-P; CD57 nanobody; )CD57 Antibody (YA4691) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD57.
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Host:
Mouse
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Application:
ELISA
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Reactivity :
Human
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Formulation:
Supplied in Phosphate-buffered solution.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|
| Dilution Ratio | 1:5000-100000 |
Product Details
CD57 Antibody (YA4691) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD57.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
Purified recombinant Human CD57
affinity purified.
Non-conjugated
Unmodified
Product Properties
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Appearance
Liquid
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Formulation
Supplied in Phosphate-buffered solution.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD57 is involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group
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Subcellular Localization
Golgi apparatus membrane; Single-pass type II membrane protein; Secreted; Golgi apparatus membrane; Single-pass type II membrane protein; Endoplasmic reticulum membrane; Secreted
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Expression
Tissue_specificity:Primarily expressed in the brain -
Isoforms & Post-Translational Modification
Q9P2W7 has 2 isomers: Q9P2W7-1: 38256 Da (predicted); Q9P2W7-2: 39738 Da (predicted).
The soluble form derives from the membrane form by proteolytic processing -
Subunit
Homodimer. Interacts with SAR1A
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SwissProt ID
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Synonyms
B3GAT1; GLCATP; Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1; Beta-1; 3-glucuronyltransferase 1; Glucuronosyltransferase P; GlcAT-P; UDP-GlcUA:glycoprotein beta-1; 3-glucuronyltransferase; GlcUAT-P; CD57 nanobody;
Documentation
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