CDKAL1 Antibody
(Synonyms: Threonylcarbamoyladenosine tRNA methylthiotransferase, CDK5 regulatory subunit-associated protein 1-like 1, tRNA-t(6)A37 methylthiotransferase, CDKAL1)CDKAL1 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to CDKAL1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:50-200 |
Product Details
CDKAL1 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to CDKAL1.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 55 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 65 kDa
Synthetic peptide corresponding to the N-term region of human CDKAL1.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CDKAL1 catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine
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Subcellular Localization
Endoplasmic reticulum membrane
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Expression
Tissue_Specificity: Expressed in pancreatic islets. -
Isoforms & Post-Translational Modification
CDKAL1 has 3 isoforms, Q5VV42-1: amino acid length is 579, molecular weight is 65111 Da (predicted); Q5VV42-2: amino acid length is 488, molecular weight is 54667 Da (predicted); Q5VV42-3: amino acid length is 97, molecular weight is 11043 Da (predicted).
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SwissProt ID
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Synonyms
Threonylcarbamoyladenosine tRNA methylthiotransferase, CDK5 regulatory subunit-associated protein 1-like 1, tRNA-t(6)A37 methylthiotransferase, CDKAL1
Documentation
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