p57 Kip2 Antibody (YA4058)
(Synonyms: BWS; WBS; p57; BWCR; KIP2; p57Kip2)p57 Kip2 Antibody (YA4058) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to p57 Kip2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, IHC-P, ICC/IF, FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:200-1:1000 | 1:200-1:1000 | 1:200-1:400 | 1:10000 |
Product Details
p57 Kip2 Antibody (YA4058) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to p57 Kip2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 57 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 32 kDa
Purified recombinant fragment of human CDKN1C aa 217-316.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
p57 Kip2 is a Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life
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Subcellular Localization
Nucleus
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Expression
Tissue_specificity:This substance is expressed in the heart, brain, lungs, skeletal muscle, kidneys, pancreas, and testes. It is also expressed in the eyes. Higher concentrations are found in the placenta, while lower concentrations are found in the liver. -
Isoforms & Post-Translational Modification
P49918 has 2 isomers: P49918-1: 32177 Da (predicted); P49918-2: 31040 Da (predicted).
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Subunit
Interacts with PCNA
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SwissProt ID
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Synonyms
BWS; WBS; p57; BWCR; KIP2; p57Kip2
Documentation
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