CHM Antibody (YA6507)

Cat. No.: HY-P86814: Data Sheet User Guide for Antibodies
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CHM Antibody (YA6507) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CHM.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

CHM Antibody (YA6507) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CHM.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 73 kDa;

Observed band size: 105 kDa 2O and PBS, and then probed with the primary antibody (HA720064, 1/200) for 30 minutes at room temperature. The detection was performed using a

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P24386

Gene ID

1121 [NCBI]

Immunogen

Synthetic peptide within human CHM aa 36-85/653.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:200
FC FC: Flow Cytometry	1:500-1:1000

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation

Subcellular Localization：Cytoplasm, cytosol

Isoforms & Post-Translational Modification：P24386 has two isomers: P24386-1: 73476 Da (predicted); P24386-2: 12301 Da (predicted).

Subunit：Monomer (By similarity)

Synonyms

CHM antibody; Chm antibody; Choroideraemia protein antibody; Choroideremia antibody; DXS540 antibody; FLJ38564 antibody; GGTA antibody; HSD 32 antibody; MGC102710 antibody; Rab escort protein 1 antibody; CHM antibody; Chm antibody; Choroideraemia protein antibody; Choroideremia antibody; DXS540 antibody; FLJ38564 antibody; GGTA antibody; HSD 32 antibody; MGC102710 antibody; Rab escort protein 1 antibody; Rab geranylgeranyltransferase component A antibody; Rab proteins geranylgeranyltransferase component A 1 antibody; RAE1_HUMAN antibody; REP 1 antibody; REP-1 antibody; REP1 antibody; TCD antibody; TCD protein antibody;

Documentation

User Guide for Antibodies (1077 KB)