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Collagen 18 alpha 1 Antibody

(Synonyms: Collagen alpha-1(XVIII) chain, COL18A1)
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Collagen 18 alpha 1 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Collagen 18 alpha 1.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P, ICC/IF

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.

  • Conjugation:
    Non-conjugated
  • Collagen 18 alpha 1 Antibody Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
Dilution Ratio 1:500-1000 1:100-200 1:100-500

Product Details

Description

Collagen 18 alpha 1 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Collagen 18 alpha 1.

  • Host Rabbit
  • Clonality Polyclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 178; 136 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 178 kDa
Immunogen

Synthetic peptide corresponding to the center region of human Collagen 18 alpha 1.

Sensitivity

Endogenous

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Collagen 18 alpha 1 is a Probably plays a major role in determining the retinal structure as well as in the closure of the neural tube

  • Subcellular Localization

    Secreted, extracellular space, extracellular matrix; Secreted, extracellular space, extracellular matrix, basement membrane

  • Expression


    Tissue_Specificity: Detected in placenta (at protein level). Present in multiple organs with highest levels in liver, lung and kidney.

  • Isoforms & Post-Translational Modification

    Collagen 18 alpha 1 has 3 isoforms, P39060-3: amino acid length is 1754, molecular weight is 178188 Da (predicted); P39060-1: amino acid length is 1519, molecular weight is 154018 Da (predicted); P39060-2: amino acid length is 1339, molecular weight is 135761 Da (predicted).
    Prolines at the third position of the tripeptide repeating unit (G-X-Y) of the triple-helical regions are hydroxylated.

  • Subunit

    Forms homotrimers.

  • SwissProt ID

    P39060

  • Gene ID
    80781 [NCBI]
  • Synonyms

    Collagen alpha-1(XVIII) chain, COL18A1

Collagen 18 alpha 1 Antibody Related Classifications

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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • Collagen 18 alpha 1 Antibody Product Image