Collagen 7 alpha 1 Antibody
(Synonyms: Collagen alpha-1(VII) chain, Long-chain collagen, LC collagen, COL7A1)Collagen 7 alpha 1 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Collagen 7 alpha 1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 | 1:100-500 |
Product Details
Collagen 7 alpha 1 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Collagen 7 alpha 1.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 295 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 295 kDa
Synthetic peptide corresponding to the center region of human Collagen 7 alpha 1.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Collagen 7 alpha 1 is a Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen
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Subcellular Localization
Secreted, extracellular space, extracellular matrix, basement membrane
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Isoforms & Post-Translational Modification
Collagen 7 alpha 1 has 2 isoforms, Q02388-1: amino acid length is 2944, molecular weight is 295220 Da (predicted); Q02388-2: amino acid length is 2912, molecular weight is 292267 Da (predicted).三肽重复单元(G-X-Y)中第三位的脯氨酸在部分或所有链中会被羟基化Collagen 7 alpha 1 存在 2 个异构体,Q02388-1:氨基酸个数为 2944 个,分子量为 295220 Da (预测);Q02388-2:氨基酸个数为 2912 个,分子量为 292267 Da (预测)。Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains
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Subunit
Homotrimer.
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SwissProt ID
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Synonyms
Collagen alpha-1(VII) chain, Long-chain collagen, LC collagen, COL7A1
Documentation