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Cat. No.: HY-P86819

COMMD10 Antibody (YA6512)

Name: COMMD10 Antibody (YA6512)
Brand: MedChemExpress
SKU: HY-P86819
Availability: PreOrder

(Synonyms: COMM domain-containing protein 10 COMMD10 HSPC305 PTD002)

COMMD10 Antibody (YA6512) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to COMMD10.

For research use only. We do not sell to patients.

Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	IHC-P IHC-P: Immunohistochemistry-Paraffin	IP IP: Immunoprecipitation
Dilution Ratio	1:2000	1:50	1-2μg/sample

Description

COMMD10 Antibody (YA6512) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to COMMD10.

Host Rabbit
Clonality Recombinant,Monoclonal
Species Reactivity
Human
Observed Molecular Weight

Observed band size: 25 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 23 kDa

Immunogen

Recombinant protein within human COMMD10 aa 1-202.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

COMMD10 is a Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex. May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B^[1]^[2]^[3]^[4].
Subcellular Localization

Cytoplasm,Nucleus
Expression

Tissue_Specificity: Ubiquitous
Subunit

Component of the commander complex consisting of the CCC subcomplex and the retriever subcomplex (PubMed:37172566, PubMed:38459129, PubMed:38459129, PubMed:25355947, PubMed:15799966)
SwissProt ID

Q9Y6G5
Gene ID

51397 [NCBI]
Synonyms

COMM domain-containing protein 10 COMMD10 HSPC305 PTD002