Complex III Subunit 7 Antibody (YA2358)(PBS only)

Cat. No.: HY-P82613A: Data Sheet User Guide for Antibodies
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Complex III Subunit 7 Antibody (YA2358) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Complex III Subunit 7.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Complex III Subunit 7 Antibody (YA2358) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Complex III Subunit 7.

Host

Rabbit

Molecular Weight

Predicted band size: 14 kDa;

Observed band size: 14 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Rat

SwissProt ID

P14927

Gene ID

7381 [NCBI]

Immunogen

Recombinant protein of human UQCRB aa2-111.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
IP IP: Immunoprecipitation	1:20

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c

Subcellular Localization：Mitochondrion inner membrane; Peripheral membrane protein; Matrix side

Isoforms & Post-Translational Modification：P14927 has 2 isomers: P14927-1: 13530 Da (predicted); P14927-2: 16267 Da (predicted).

Subunit：Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits.

Research Field

Cardiovascular

Synonyms

QPC; QCR7; QP-C; UQBC; UQBP; UQPC; UQCR6; MC3DN3

Documentation

User Guide for Antibodies (1077 KB)