CPI17 Antibody (YA10011)
(Synonyms: CPI17, PPP1INL, PPP1R14A, Protein phosphatase 1 regulatory subunit 14A, 17 kDa PKC-potentiated inhibitory protein of PP1, Protein kinase C-potentiated inhibitor protein of 17 kDa, CPI-17)CPI17 Antibody (YA10011) is a Rabbit-derived and non-conjugated IgG Monoclonal, Recombinant antibody, targeting to CPI17.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, IP
-
Reactivity :
Human, Mouse, Rat
-
Formulation:
Supplied in PBS (pH 7.4), containing 50% glycerol, 0.05% BSA, and 0.05% Proclin300.
-
Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
|
IP
IP: Immunoprecipitation
|
|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:10-50 |
Product Details
CPI17 Antibody (YA10011) is a Rabbit-derived and non-conjugated IgG Monoclonal, Recombinant antibody, targeting to CPI17.
-
Host Rabbit
-
Clonality Monoclonal,Recombinant
-
Species ReactivityHuman, Mouse, Rat
-
Observed Molecular WeightObserved band size: 17 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 16 kDa
Synthetic peptide corresponding to human CPI17 protein.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in PBS (pH 7.4), containing 50% glycerol, 0.05% BSA, and 0.05% Proclin300.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
CPI17 is an Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction
-
Subcellular Localization
Cytoplasm
-
Expression
Tissue_Specificity: Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta. -
Isoforms & Post-Translational Modification
CPI17 has 2 isoforms, Q96A00-1: amino acid length is 147, molecular weight is 16693 Da (predicted); Q96A00-2: amino acid length is 120, molecular weight is 13480 Da (predicted).
-
SwissProt ID
-
Synonyms
CPI17, PPP1INL, PPP1R14A, Protein phosphatase 1 regulatory subunit 14A, 17 kDa PKC-potentiated inhibitory protein of PP1, Protein kinase C-potentiated inhibitor protein of 17 kDa, CPI-17
Documentation