M-CSF Antibody (YA3728)
(Synonyms: MCSF)M-CSF Antibody (YA3728) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to M-CSF.
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Host:
Mouse
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Isotype:
IgG
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Application:
IHC-P, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:10000 |
Product Details
M-CSF Antibody (YA3728) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to M-CSF.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 43 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 60 kDa
Purified recombinant fragment of human CSF1 aa 33-496.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS with 0.05% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Macrophage colony-stimulating factor (M-CSF), also known as colony-stimulating factor-1 (CSF-1), is a hemopoietic growth factor that regulates the survival, proliferation, differentiation and function of the cells of the mononuclear phagocyte lineage. M-C
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Subcellular Localization
Cell membrane; Single-pass type I membrane protein; Secreted, extracellular space
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Isoforms & Post-Translational Modification
P09603 has 3 isomers: P09603-1: 60179 Da (predicted); P09603-2: 47903 Da (predicted); P09603-3: 29215 Da (predicted).
N-glycosylated;N-glycosylated;N-glycosylated;O-glycosylated; contains chondroitin sulfate (PubMed:1531650, PubMed:8051056). O-glycosylated with core 1 or possibly core 8 glycans (PubMed:22171320, PubMed:23234360, PubMed:3264877);O-glycosylated -
Subunit
Homodimer or heterodimer; disulfide-linked (PubMed:1531650, PubMed:3264877, PubMed:8422357). Likely to exist in multiple forms: homodimer consisting of 2 identical 150-200 kDa proteoglycan subunits, heterodimer consisting of a 150-200 kDa proteoglycan subunit and a truncated 43 kDa subunit, and homodimer consisting of 2 identical 43 kDa subunits (PubMed:8051056). Interacts with CSF1R (PubMed:20504948)
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SwissProt ID
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Synonyms
MCSF
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