CSF1 - colony stimulating factor 1 Gene

Also Known as MCSF; CSF-1

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 1435

About CSF1

Cytogenetic location: 1p13.3 Genomic coordinates (GRCh38): 1:109,910,506-109,930,992 (from NCBI)

This gene has 9 transcripts (splice variants) and 215 orthologues. Ubiquitous expression in placenta (RPKM 19.9), spleen (RPKM 19.7) and 25 other tissues.

Summary

The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]

CSF1 Products (4)

mRNA	Protein	Name
NM_000757.6	NP_000748.4	macrophage colony-stimulating factor 1 isoform a precursor
NM_172210.3	NP_757349.2	macrophage colony-stimulating factor 1 isoform b precursor
NM_172211.4	NP_757350.2	macrophage colony-stimulating factor 1 isoform c precursor
NM_172212.3	NP_757351.2	macrophage colony-stimulating factor 1 isoform a precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables cytokine activity	IDA IDA: Inferred from direct assay	2460758	GOA
enables growth factor activity	IDA IDA: Inferred from direct assay	2460758	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	22153499	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	22153499	GOA
enables protein homodimerization activity	IDA IDA: Inferred from direct assay	3264878	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in cell surface receptor protein tyrosine kinase signaling pathway	IDA IDA: Inferred from direct assay	19100238	GOA
involved in osteoclast differentiation	IDA IDA: Inferred from direct assay	18606301	GOA
acts upstream of or within positive regulation of cell population proliferation	IDA IDA: Inferred from direct assay	10652277	GOA
involved in positive regulation of gene expression	IDA IDA: Inferred from direct assay	1739124	GOA
involved in positive regulation of macrophage chemotaxis	IDA IDA: Inferred from direct assay	19100238	GOA
involved in positive regulation of macrophage colony-stimulating factor signaling pathway	IDA IDA: Inferred from direct assay	19100238	GOA
involved in positive regulation of macrophage derived foam cell differentiation	IDA IDA: Inferred from direct assay	17244792	GOA
involved in positive regulation of macrophage differentiation	IDA IDA: Inferred from direct assay	2460758	GOA
involved in positive regulation of macrophage migration	IMP IMP: Inferred from mutant phenotype	24415783	GOA
involved in positive regulation of microglial cell migration	IDA IDA: Inferred from direct assay	19100238	GOA
involved in positive regulation of mononuclear cell proliferation	IDA IDA: Inferred from direct assay	2460758	GOA
involved in positive regulation of osteoclast differentiation	IDA IDA: Inferred from direct assay	15304486	GOA
involved in positive regulation of protein metabolic process	IDA IDA: Inferred from direct assay	1739124	GOA
involved in response to ischemia	IDA IDA: Inferred from direct assay	8922060	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in extracellular space	IDA IDA: Inferred from direct assay	2460758	GOA
located in perinuclear region of cytoplasm	IDA IDA: Inferred from direct assay	1739124	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CSF1 Protein Structure

CSF-1

0
100
200
300
400
500
554 a.a.

Protein Preferred Names	Protein Names
macrophage colony-stimulating factor 1	colony stimulating factor 1 (macrophage)

CSF1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	CSF1	P09603	KRTAP10-8	Homo sapiens	P60410	Y2H Prey Pooling	32296183
Intra	CSF1	P09603	KRTAP10-8	Homo sapiens	P60410	Y2H Array	32296183
Intra	CSF1	P09603	KRTAP10-8	Homo sapiens	P60410	Validated Y2H	32296183
Intra	CSF1	P09603	MTUS2	Homo sapiens	Q5JR59-3	Y2H Array	32296183
Intra	CSF1	P09603	MTUS2	Homo sapiens	Q5JR59-3	Y2H Prey Pooling	32296183
Intra	CSF1	P09603	MTUS2	Homo sapiens	Q5JR59-3	Validated Y2H	32296183
Intra	CSF1	P09603	KRTAP1-1	Homo sapiens	Q07627	Validated Y2H	32296183
Intra	CSF1	P09603	KRTAP1-1	Homo sapiens	Q07627	Y2H Array	32296183
Intra	CSF1	P09603	KRTAP1-1	Homo sapiens	Q07627	Y2H Prey Pooling	32296183
Intra	CSF1	P09603	CSF1R	Homo sapiens	P07333	ITC	22153499
Intra	CSF1	P09603	CSF1R	Homo sapiens	P07333	TEM	22153499
Intra	CSF1	P09603	CSF1R	Homo sapiens	P07333	Light Scattering	22153499
Intra	CSF1	P09603	CSF1R	Homo sapiens	P07333	FFF	22153499
Intra	CSF1	P09603	CSF1R	Homo sapiens	P07333	X-Ray Diffraction	26235028
Intra	CSF1	P09603	CSF1R	Homo sapiens	P07333	GMS	22153499
Intra	CSF1	P09603	CSF1R	Homo sapiens	P07333	GMS	26235028
Intra	CSF1	P09603	CSF1R	Homo sapiens	P07333	SAXS	22153499
Intra	CSF1	P09603	CSF1R	Homo sapiens	P07333	SAXS	26235028
Intra	CSF1	P09603	CSF1R	Homo sapiens	P07333	ITC	22902366
Intra	CSF1	P09603	SGTA	Homo sapiens	O43765	Validated Y2H	25416956
Intra	CSF1	P09603	CSF1	Homo sapiens	P09603	Light Scattering	22902366
Intra	CSF1	P09603	CSF1	Homo sapiens	P09603	FFF	22153499
Intra	CSF1	P09603	CSF1	Homo sapiens	P09603	Comigration in SDS	22153499
Intra	CSF1	P09603	CSF1	Homo sapiens	P09603	GMS	22153499
Intra	CSF1	P09603	SGTA	Homo sapiens	O43765	Y2H Prey Pooling	32296183
Intra	CSF1	P09603	SGTA	Homo sapiens	O43765	Y2H Array	32296183
Intra	CSF1	P09603	CSF1	Homo sapiens	P09603	X-Ray Diffraction	22902366
Intra	CSF1	P09603	CSF1	Homo sapiens	P09603	FFF	22902366
Intra	CSF1	P09603	CSF1	Homo sapiens	P09603	GMS	22902366
Intra	CSF1	P09603	CSF1	Homo sapiens	P09603	Light Scattering	22153499
Intra	CSF1	P09603	CYSRT1	Homo sapiens	A8MQ03	Y2H Array	32296183
Intra	CSF1	P09603	CYSRT1	Homo sapiens	A8MQ03	Y2H Prey Pooling	32296183
Cross	CSF1	P09603	Csf1r	Mus musculus	P09581	ITC	22826234
Intra	CSF1	P09603	FHL3	Homo sapiens	Q13643	Y2H Array	25416956
Intra	CSF1	P09603	FHL3	Homo sapiens	Q13643	Y2H Prey Pooling	25416956
Intra	CSF1	P09603	NOTCH2NLA	Homo sapiens	Q7Z3S9	Validated Y2H	25416956
Intra	CSF1	P09603	NOTCH2NLA	Homo sapiens	Q7Z3S9	Y2H Array	25416956
Cross	CSF1	P09603	barf1_ebvb9	Epstein-Barr virus	P03228	FFF	22902366
Cross	CSF1	P09603	barf1_ebvb9	Epstein-Barr virus	P03228	GMS	22902366
Cross	CSF1	P09603	barf1_ebvb9	Epstein-Barr virus	P03228	SAXS	22902366
Cross	CSF1	P09603	barf1_ebvb9	Epstein-Barr virus	P03228	ITC	22902366
Cross	CSF1	P09603	barf1_ebvb9	Epstein-Barr virus	P03228	SPR	22902366
Cross	CSF1	P09603	barf1_ebvb9	Epstein-Barr virus	P03228	TEM	22902366
Cross	CSF1	P09603	barf1_ebvb9	Epstein-Barr virus	P03228	Light Scattering	22902366
Cross	CSF1	P09603	barf1_ebvb9	Epstein-Barr virus	P03228	X-Ray Diffraction	22902366
Cross	CSF1	P09603	BARF1	Epstein-Barr virus	P0CW72	GMS	22826234
Cross	CSF1	P09603	BARF1	Epstein-Barr virus	P0CW72	ITC	22826234
Cross	CSF1	P09603	BARF1	Epstein-Barr virus	P0CW72	X-Ray Diffraction	22826234

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CSF1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7050A	M-CSF Protein, Human (CHO)	P09603-3 (E33-S190)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P7050	M-CSF Protein, Human	P09603-3 (E33-S190)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P70488	M-CSF Protein, Human (223a.a, HEK293, His)	P09603-1 (E33-R255)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P73287	M-CSF Protein, Human (Biotinylated, HEK293, His)	P09603-1 (E33-N190)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P73827	M-CSF Protein, Human (HEK293, His)	P09603-1 (E33-N190)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P73829	M-CSF Protein, Human (HEK293, Fc)	P09603-1/NP_757349.1 (E33-R255)	≥ 90%, as determined by reducing SDS-PAGE.
HY-P77516	M-CSF Protein, Human (Biotinylated, HEK293)	P09603-1/NP_757349.1 (E33-R255)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P78427	M-CSF Protein, Human (HEK293, His-Avi)	P09603-1 (E33-N190)	≥ 95%, as determined by Bis-Tris PAGE.
HY-P78836	M-CSF Protein, Human (Biotinylated, HEK293, His-Avi)	P09603-1 (E33-R255)	≥ 90%, as determined by reducing SDS-PAGE.
HY-P700137AF	Animal-Free M-CSF Protein, Human (His)	NP_757350.2 (E33-S190)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P700788	M-CSF Protein, Human (Biotinylated, HEK293, C-His-Avi)	P09603-1 (E33-N190)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P701101	M-CSF Protein, Human (CHO,Tag Free)	P09603-1 (E33-N190)	≥ 95%, as determined by reducing SDS-PAGE.

CSF1 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P80750	M-CSF Antibody (YA301)	WB, IHC-F, IHC-P, ICC/IF	Human
HY-P80750A	M-CSF Antibody (YA301)(PBS only)	WB, IHC-F, IHC-P, ICC/IF	Human
HY-P84031	M-CSF Antibody (YA3728)	IHC-P, ELISA	Human
HY-P84031A	M-CSF Antibody (YA3728)(PBS only)	IHC-P, ELISA	Human
HY-P85271	M-CSF Antibody (YA4963)	WB, IHC-P, ICC/IF, ELISA	Human

Related Diseases

Diseases	Alias
Pigmented Villonodular Synovitis	Diffuse Giant Cell Tumor Of Tenosynovium Villous Tenosynovitis Diffuse Pigmented Villonodular Synovitis Diffuse-Type Gct Diffuse-Type Giant Cell Tumor Localized Pigmented Villonodular Synovitis Tgct Tsgct Tenosynovial Giant Cell Tumor Tenosynovial Giant Cell Tumors Synovitis Pigmented Villonodular Synovitis, Pigmented Villonodular Fibrous Histiocytoma Of Tendon Sheath Testicular Germ Cell Tumor Chronic Haemorrhagic Villous Synovitis Pvns - [Pigmented Villonodular Synovitis] Villonodular Synovitis
Benign Giant Cell Tumor	Giant Cell Tumors
Pulmonary Alveolar Proteinosis
Monocytic Leukemia	Monocytic Leukaemia Schilling'S Leukaemia Schilling'S Leukemia M5b Acute Differentiated Monocytic Leukemia
Osteopetrosis	Marble Bone Disease Albers-Schonberg Disease Osteopetroses Marble Bones Osteopetrosis And Related Disorders Congenital Osteopetrosis Marble Bone Albers-Schoenberg Disease Albers-Schonberg Osteopetrosis Osteosclerosis Fragilis Ivory Bones
Adult-Onset Still'S Disease	Adult-Onset Still Disease Adult Onset Still'S Disease Adult Still'S Disease Still'S Disease Adult Onset Aosd Wissler-Fanconi Syndrome Stills Disease Adult-Onset Still'S Disease, Adult-Onset Wissler'S Syndrome
Fibrosarcoma Of Bone	Malignant Histiocytosis Malignant Fibroxanthoma Malignant Fibrous Histiocytoma Histiocytic Medullary Reticulosis Nasal Type Extranodal Nk/T-Cell Lymphoma Histiocytic Sarcoma
Tenosynovial Giant Cell Tumor	Fibrous Histiocytoma Of Tendon Sheath Giant Cell Tumor Of Tendon Sheath Giant Cell Tumor Of Tenosynovium Giant Cell Tumour Of Tendon Sheath Giant Cell Tumour Of Tenosynovium Tenosynovial Giant Cell Tumour Diffuse-Type Gct Diffuse-Type Giant Cell Tumor Pigmented Villonodular Synovitis Tgct Tsgct
Glomerulonephritis	Bright'S Disease
Rheumatoid Arthritis	RA Arthritis, Rheumatoid Rheumatoid Arthritis, Susceptibility To Arthritis Or Polyarthritis, Rheumatic Atrophic Arthritis Rheumatism Arthritis Rheumatoid Polyarthritis
Chronic Myelomonocytic Leukemia	Leukemia, Myelomonocytic, Chronic Cmml Leukemia Myelomonocytic Chronic Cmml - [Chronic Myelomonocytic Leukaemia] Chronic Myelomonocytic Leukaemia Without Mention Of Remission Chronic Monocytic Leukaemia Chronic Monocytoid Leukaemia
Aspergillosis	Aspergillosis, Susceptibility To Infection Due To Aspergillus Aspergilloma Aspergillus Nodule Simple Aspergilloma Aspergillus Aspergillus Flavus Infection Aspergillus Fumigatus Infection Aspergillus Infection Infection By Aspergillus Fumigatus Intracavitary Aspergillus Fungus Ball Aspergillus Terreus
Pancytopenia
Bone Benign Neoplasm
Arthritis	Inflammatory Joint Disease Inflammatory Disorder Of Joint
Cherubism	CRBM Familial Benign Giant-Cell Tumor Of The Jaw Familial Fibrous Dysplasia Of Jaw Familial Multilocular Cystic Disease Of The Jaws
Nodular Tenosynovitis	Synovioma, Benign Benign Synovioma Benign Tumor Of Synovium Localized Giant Cell Tumor Of Tenosynovium Giant Cell Tumor Of Tendon Sheath
Neutropenia	Leukopenia
Leukemia, Acute Monocytic	Acute Monocytic Leukemia Acute Monoblastic Leukemia And Acute Monocytic Leukemia Acute Monocytic Leukaemia Acute Monocytic Leukaemia Without Mention Of Remission Acute Monocytic Leukemia Without Mention Of Remission Acute Monocytic Leukemia, Fab M5 Acute Monocytic Leukemia, Morphology Leukemia, Monocytic, Acute M5b Acute Differentiated Monocytic Leukemia
Aplastic Anemia	Aplastic Anemia, Susceptibility To Anemia Aplastic Idiopathic Aplastic Anemia Secondary Aplastic Anemia Idiopathic Bone Marrow Failure Aplastic Anemia Idiopathic AA Anemia, Aplastic Aplastic Anemia, Idiopathic Erythroid Aplasia Aa - [Aplastic Anaemia] Haematopoietic Aplasia Aleukia Haemorrhagica Anaemia Due To Decreased Red Cell Production Aplasia Bone Marrow Aplastic Bone Marrow Hypoplastic Anaemia Nos Myeloid Bone Marrow Aplasia Pancytopenia Panhaematopenia Hypoproliferative Anaemia Medullary Hypoplasia Red Blood Cells Hypoplastic Anaemia Panmyelophthisis Panhemocytopenia Refractive Hypoproliferative Anaemia Toxic Anaemia Toxic Aplastic Anaemia Aplastic Anaemia Due To Toxic Cause Idiopathic Aplastic Anaemia Nos
Demyelinating Disease	Demyelinating Diseases Demyelinating Disorder
Asthma	Chronic Obstructive Asthma Asthma, Diminished Response To Antileukotriene Treatment In Bronchial Hyperreactivity Asthma, Susceptibility To Asthma, Bronchial Asthma, Protection Against Asthma, Nocturnal, Susceptibility To Nocturnal Asthma Asthma-Related Traits Asthma-Related Traits, Susceptibility To Asthma, Nocturnal Chronic Obstructive Asthma With Acute Exacerbation Chronic Obstructive Asthma With Status Asthmaticus Exercise Induced Asthma Exercise-Induced Asthma Bronchial Asthma Asthma, Exercise-Induced Idiosyncratic Asthma Unspecified Asthma With Acute Exacerbation Asthma, Unspecified, With Stated Status Asthmaticus Status Asthmaticus Nos Acute Severe Asthma Acute Severe Bronchial Asthma Status Asthma Status Post Asthmaticus
Spondylarthropathy	Spondylarthropathies
Bone Disease	Bone Diseases Skeletal Disease Skeletal Disorder Disorder Of Skeletal System
Synovitis
Myelodysplastic Syndrome	Myelodysplastic Syndromes Myelodysplasia MDS Myelodysplastic Syndrome Included Myelodysplastic Syndrome, Susceptibility To, Included Myelodysplastic Syndrome, Somatic Myelodysplastic Syndrome, Susceptibility To
Leukoencephalopathy, Hereditary Diffuse, With Spheroids 1	Hereditary Diffuse Leukoencephalopathy With Spheroids Adult-Onset Leukoencephalopathy With Axonal Spheroids And Pigmented Glia Alsp Gpsc Subcortical Gliosis Of Neumann Leukoencephalopathy, Diffuse Hereditary, With Spheroids 1 Autosomal Dominant Leukoencephalopathy With Neuroaxonal Spheroids Hdls HDLS1 Leukoencephalopathy, Adult-Onset, With Axonal Spheroids And Pigmented Glia Gliosis, Familial Progressive Subcortical Leukoencephalopathy, Diffuse Hereditary, With Spheroids Pold Pigmentary Orthochromatic Leukodystrophy Hereditary Diffuse Leukoencephalopathy With Axonal Spheroids And Pigmented Glia Familial Progressive Subcortical Gliosis Leukoencephalopathy With Neuroaxonal Spheroids, Autosomal Dominant Dementia, Familial, Neumann Type Adult-Onset Leukodystrophy With Neuroaxonal Spheroids Hereditary Diffuse Leukoencephalopathy With Axonal Spheroids Neuroaxonal Leukodystrophy Fpsg Familial Dementia, Neumann Type Familial Dementia Neumann Type Leukoencephalopathy, Diffuse Hereditary, With Spheroid
Severe Congenital Neutropenia	Congenital Neutropenia Neutropenia, Severe Congenital Congenital Agranulocytosis Infantile Genetic Agranulocytosis Kostmann Disease Kostmann'S Agranulocytosis Kostmann'S Syndrome Severe Infantile Genetic Neutropenia
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Cancer Of The Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Proctitis	Ulcerative Proctitis Chronic Ulcerative Proctitis Idiopathic Proctitis Nonspecific Ulcerative Proctitis Ulcerative Colitis Confined To Rectum Ip - [Idiopathic Proctitis] Chronic Ulcerative Proctitis Nos
Histiocytic Sarcoma	Malignant Histiocytosis
Osteoporosis	Postmenopausal Osteoporosis Osteoporosis, Postmenopausal Bone Mineral Density Quantitative Trait Locus Bmnd Osteoporosis, Involutional Osteoporosis, Susceptibility To Osteoporosis, Postmenopausal, Susceptibility Bone Mineral Density Variation Qtl, Osteoporosis OSTEOP Involutional Osteoporosis Senile Osteoporosis Osteoporosis Postmenopausal Bone Mineral Density, Quantitative Trait Locus Osteoporosis, Senile Idiopathic Osteoporosis Bone Rarefaction Nos Type 1 Osteoporosis
Acute Leukemia	Stem Cell Leukaemia Stem Cell Leukemia Acute Leukemias Acute Undifferentiated Leukemia Undifferentiated Leukemia Acute Leukaemia Of Unspecified Cell Type Without Mention Of Remission Blast Cell Leukaemia Blast Leukaemia Blastic Leukaemia Undifferentiated Leukaemia
Cyclic Neutropenia	Cyclic Hematopoiesis Cyclical Neutropenia Neutropenia Cyclic Cyclic Hematopoesis Neutropenia, Cyclic Cyclic Agranulocytosis Neutropenia, Periodic Cyclic Leucopenia Periodic Neutropenia Cyclic Haematopoiesis CH Hematopoiesis, Cyclic Neutropenia, Cyclical
Endometrial Cancer	Endometrial Carcinoma Endometrial Neoplasm Malignant Neoplasm Of Endometrium Endometrioid Carcinoma Endometrial Neoplasms Carcinoma, Endometrioid Endometrial Cancer, Familial Endometrial Carcinoma, Somatic Endometrial Cancer, Susceptibility To Endometrial Ca Malignant Endometrial Neoplasm Neoplasm Of Endometrium Primary Malignant Neoplasm Of Endometrium Tumor Of Endometrium Carcinoma Of The Endometrium Endometrioid Carcinoma Of Female Reproductive System ENDMC Carcinoma Endometrioid Endometrial Cancers Cancer, Endometrial Uterine Corpus Cancer
Blau Syndrome	Arthrocutaneouveal Granulomatosis Jabs Syndrome BLAUS Sarcoidosis, Early-Onset Acug Granulomatous Inflammatory Arthritis, Dermatitis, And Uveitis, Familial Eos Granulomatosis, Familial Juvenile Systemic Granulomatosis, Familial, Blau Type Familial Juvenile Systemic Granulomatosis Early Onset Sarcoidosis Synovitis Granulomatous With Uveitis And Cranial Neuropathies Early-Onset Sarcoidosis Familial Granulomatosis, Blau Type Pediatric Granulomatous Arthritis Familial Granulomatosis Blau Type Familial Granulomatous Inflammatory Arthritis Dermatitis And Uveitis Synovitis, Granulomatous, With Uveitis And Cranial Neuropathies
Acute Promyelocytic Leukemia	Leukemia, Acute Promyelocytic Acute Myeloblastic Leukemia Type 3 Aml M3 APL Leukemia, Acute Promyelocytic, Somatic Aml With T(15 17)(Q22 Q12) (Pml/Raralpha) And Variants Apml Acute Myeloblastic Leukemia 3 Acute Myeloid Leukemia With T(15 17)(Q22 Q12) (Pml/Raralpha) And Variants Acute Myeloblastic Leukaemia Type 3 Acute Myeloid Leukaemia M3 Acute Myeloid Leukemia M3 Acute Promyelocytic Leukaemia M3 Anll Myeloid Leukemia, Acute, M3 Leukemia Promyelocytic Acute Leukemia, Promyelocytic, Acute Leukemia, Acute, Promyelocytic
Connective Tissue Benign Neoplasm	Soft Tissue Neoplasms Mesenchymal Tissue Neoplasm Neoplasm Of Soft Tissue Neoplasm Of Soft Tissues Soft Tissue Benign Neoplasm Tumor Of The Soft Tissue Soft Tissue Neoplasm
Osteopetrosis, Autosomal Recessive 2	OPTB2 Autosomal Recessive Osteopetrosis 2 Osteopetrosis, Mild Autosomal Recessive Form Osteoclast-Poor Osteopetrosis Osteopetrosis, Osteoclast-Poor Mild Autosomal Recessive Form Osteopetrosis Osteopetrosis Autosomal Recessive 2 Autosomal Recessive Osteopetrosis Type 2 Osteopetrosis Osteoclast-Poor Osteopetrosis, Autosomal Recessive, Type 2
Langerhans Cell Histiocytosis	Histiocytosis X Lch Langerhans Cell Granulomatosis Langerhans-Cell Histiocytosis Letterer-Siwe Disease Hashimoto-Pritzger Disease Histiocytosis, Langerhans-Cell Langerhan'S Cell Histiocytosis Letterer-Siwe Disease Involving Intra-Abdominal Lymph Nodes Letterer-Siwe Disease Involving Intrapelvic Lymph Nodes Letterer-Siwe Disease Involving Intrathoracic Lymph Nodes Letterer-Siwe Disease Involving Lymph Nodes Of Axilla And Upper Limb Letterer-Siwe Disease Involving Lymph Nodes Of Head, Face And Neck Letterer-Siwe Disease Involving Lymph Nodes Of Head, Face, And Neck Letterer-Siwe Disease Involving Lymph Nodes Of Inguinal Region And Lower Limb Letterer-Siwe Disease Involving Lymph Nodes Of Multiple Sites Letterer-Siwe Disease Involving Spleen Letterer-Siwe Disease Of Intra-Abdominal Lymph Nodes Letterer-Siwe Disease Of Intrapelvic Lymph Nodes Letterer-Siwe Disease Of Intrathoracic Lymph Nodes Letterer-Siwe Disease Of Lymph Nodes Of Axilla And Upper Limb Letterer-Siwe Disease Of Lymph Nodes Of Axilla And/Or Upper Limb Letterer-Siwe Disease Of Lymph Nodes Of Head, Face And Neck Letterer-Siwe Disease Of Lymph Nodes Of Head, Face And/Or Neck Letterer-Siwe Disease Of Lymph Nodes Of Inguinal Region Amd/Or Lower Limb Letterer-Siwe Disease Of Lymph Nodes Of Inguinal Region And Lower Limb Letterer-Siwe Disease Of Lymph Nodes Of Inguinal Region And/Or Lower Limb Letterer-Siwe Disease Of Lymph Nodes Of Multiple Sites Letterer-Siwe Disease Of Spleen Familial Letterer-Siwe Disease Langerhans-Cell Histiocytosis Nos
Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy 1	Nasu-Hakola Disease Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy Plosl Nhd Presenile Dementia With Bone Cysts Plo-Sl PLOSL1 Dementia, Prefrontal, With Bone Cysts Dementia, Progressive, With Lipomembranous Polycystic Osteodysplasia Brain-Bone-Fat Disease Progressive Dementia With Lipomembranous Polycystic Osteodysplasia Brain-Bone-Fat Disease
Systemic Lupus Erythematosus	Lupus Nephritis SLE Disseminated Lupus Erythematosus Systemic Lupus Erythematosus, Susceptibility To Lupus Erythematosus, Systemic Lupus Nephritis, Susceptibility To Libman-Sacks Disease Systemic Lupus Erythematosus Susceptibility To Sle - Lupus Erythematosus, Systemic Le Syndrome Lupus Lupus Erythematosus Systemic Lupus Erythematosus, Systemic, Susceptibility To Lupus Vulgaris Lupus Erythematosus, Discoid Lupus Erythematosus Systemic Lupus Erythematosus Nos Sle - [Systemic Lupus Erythematosus]
Bone Giant Cell Tumor	Giant Cell Tumor Of Bone Osteoclastoma Gct Of Bone Bone Giant Cell Tumour Giant Cell Myeloma Giant Cell Neoplasm Of Bone Giant Cell Tumour Of Bone
Multiple Sclerosis	MS Multiple Sclerosis, Susceptibility To Disseminated Sclerosis Multiple Sclerosis, Disease Progression, Modifier Of Insular Sclerosis Multiple Sclerosis Modifier Of Disease Progression Multiple Sclerosis, Susceptibility To 1 Multiple Sclerosis, Susceptibility To, 1 Multiple Sclerosis 1 Generalized Multiple Sclerosis Multiple Sclerosis Variant Multiple Sclerosis Susceptibility To Cerebrospinal Sclerosis Generalised Multiple Sclerosis Ms - [Multiple Sclerosis] Disseminated Cerebrospinal Sclerosis Disseminated Multiple Sclerosis Disseminated Nervous System Myelosclerosis Multiple Cerebrospinal Sclerosis Multiple Combined Sclerosis Multiple Sclerosis Generalised Disseminated Brain Sclerosis Disseminated Spinal Sclerosis Insular Brain Sclerosis Miliary Brain Sclerosis Multiple Combined Sclerosis Of Spinal Cord Multiple Ascending Sclerosis Multiple Brain Sclerosis Multiple Sclerosis Of Brain Stem Multiple Sclerosis Of The Brain Stem Multiple Sclerosis Of Cord Sclérose En Plaques Plaque Sclerosis Multiple Sclerosis Of The Spinal Cord
Malignant Giant Cell Tumor Of The Tendon Sheath	Giant Cell Tumour Of Tendon Sheath, Malignant Malignant Giant Cell Neoplasm Of The Tendon Sheath
Type 1 Diabetes Mellitus	Diabetes Mellitus, Insulin-Dependent Diabetes Mellitus Type 1 IDDM Type 1 Diabetes Insulin-Dependent Diabetes Mellitus T1D Juvenile-Onset Diabetes Jod Diabetes Mellitus, Type 1 Diabetes Mellitus, Insulin-Dependent-1 Type I Diabetes Mellitus Autoimmune Diabetes Juvenile Diabetes Juvenile-Onset Diabetes Mellitus Diabetes, Insulin Dependent Insulin-Dependent Diabetes Mellitus-1 Diabetes Mellitus Insulin-Dependent Diabetes Autoimmune Diabetes Mellitus, Insulin-Dependent, Susceptibility To Diabetes Mellitus, Type 1, Susceptibility To Diabetes Type 1 Type I Diabetes Diabetes, Autoimmune T1dm - [Type 1 Diabetes Mellitus] Iddm - [Insulin Dependent Diabetes Mellitus] Type 1 Iddm Juvenile Diabetes Mellitus Without Compications Idiopathic Insulin-Dependent Diabetes Mellitus Without Complications Juvenile-Onset Diabetes Mellitus Without Compications Ketosis-Prone Diabetes Mellitus Without Compications Juvenile-Onset-Type Diabetes Mellitus Without Compications
Baritosis	Deposition Of Barium In The Lungs Inhalation Of Barytes
Breast Cancer	Breast Carcinoma Male Breast Cancer Breast Cancer, Familial Malignant Neoplasm Of Breast Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Urethra Transitional Cell Carcinoma	Urethral Transitional Cell Carcinoma Urethral Urothelial Carcinoma
Melanoma	Malignant Melanoma Cutaneous Melanoma Naevocarcinoma Malignant Melanomas
Hematologic Cancer	Hematologic Neoplasm Hematologic Neoplasms Hematologic Malignancies Blood Cancer Hematologic Malignancy Hematological Tumors Hematopoietic And Lymphoid System Tumor Hematopoietic Cancer Hematopoietic Neoplasm Hematopoietic Tumors Malignant Hematopoietic Neoplasm Liquid Tumor Hematopoietic Neoplasms
Synovium Neoplasm	Synovial Neoplasm Tumor Of Synovium
Pancreatic Cancer	Pancreatic Carcinoma Carcinoma Of Pancreas Familial Pancreatic Carcinoma Pancreatic Neoplasm Pancreatic Carcinoma, Familial Malignant Neoplasm Of Pancreas Pancreatic Acinar Carcinoma Pancreatic Tumor Familial Pancreatic Cancer Neoplasm Of The Pancreas Cancer Of The Pancreas Pancreatic Carcinoma, Somatic Pancreatic Cancer, Somatic Ca Body Of Pancreas Ca Head Of Pancreas Ca Tail Of Pancreas Malignant Neoplasm Of Body Of Pancreas Malignant Neoplasm Of Head Of Pancreas Malignant Neoplasm Of Tail Of Pancreas Pancreas Neoplasm Exocrine Cancer Exocrine Pancreas Carcinoma Hereditary Pancreatic Cancer Hereditary Pancreatic Carcinoma PNCA Pancreatic Cancer, Susceptibility To Carcinoma Of Head Of Pancreas Pancreatic Neoplasms Pancreatic Tumors Cancer, Pancreatic Cancer Of Pancreas Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Susceptibility To Lung Cancer, Protection Against Adenocarcinoma Of Lung, Somatic Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
Immune Deficiency Disease	Immunodeficiency Primary Immunodeficiency Primary Immunodeficiency Disease Immunologic Deficiency Syndromes Hypoimmunity Immune Deficiency Disorder Immunodeficiency Syndrome Immune Disorder Primary Immune Deficiency Disorder Immune System Diseases Human Immunodeficiency Virus Infection Hiv - [Human Immunodeficiency Virus Infection] Hiv Positive Nos Hiv Disease Acquired Immune Deficiency Syndrome-Related Complex Aids-Like Syndrome Aids-Related Complex Nos Arc - [Aids-Related Complex] Immunodeficiency Due To Human Immunodeficiency Virus Infection Unspecified Human Immunodeficiency Virus Disease Hiv Disease Nos Human Immunodeficiency Virus Positive Nos Hiv Nos Deficiency Of Complement Initial Pathway Deficiency Of Complement Terminal Pathway Cfdd - [Complement Factor D Deficiency] Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency Nonfamilial Hypogammaglobulinaemia Common Variable Immune Deficiency Nonfamilial Agammaglobulinaemia Common Variable Agammaglobulinaemia Agammaglobulinaemia Nos Agammaglobulinaemia Antibody Deficiency Syndrome Hypogammaglobulinaemia Antibody Deficiency Syndrome Acquired Agammaglobulinaemia Nos Hypogammaglobulinaemia Nos Hyper Igm
Severe Combined Immunodeficiency	Scid Severe Combined Immunodeficiency Disease Combined T And B Cell Inborn Immunodeficiency Immunodeficiency, Severe Combined Scid - [Severe Combined Immunodeficiencies]
Breast Adenocarcinoma	Mammary Adenocarcinoma Adenocarcinoma Of Breast
Renal Cell Carcinoma, Nonpapillary	Renal Cell Carcinoma RCC Nonpapillary Renal Cell Carcinoma Clear Cell Renal Cell Carcinoma Hypernephroma Adenocarcinoma Of Kidney Renal Carcinoma, Chromophobe, Somatic Clear Cell Carcinoma Of Kidney Clear-Cell Metastatic Renal Cell Carcinoma Clear Cell Renal Carcinoma Renal Cell Carcinoma, Somatic Conventional Renal Cell Carcinoma Conventional Renal Cell Carcinoma Renal Clear Cell Carcinoma Ccrcc Hereditary Clear Cell Renal Cell Carcinoma Carcinoma, Renal Cell Renal Cell Carcinoma, Clear Cell, Somatic Renal Cell Carcinoma, Clear Cell Clear Cell Kidney Carcinoma Clear Cell Rcc Cystic-Multilocular Variant Clear Cell Renal Cell Adenocarcinoma Hereditary Clear Cell Renal Cell Adenocarcinoma Common Renal Cell Carcinoma Crcc Renal Cell Carcinoma Non-Papillary Carcinoma Renal Cell Renal Cell Cancer Carcinoma, Renal Cell, Nonpapillary
Refractory Plasma Cell Neoplasm
Amyotrophic Lateral Sclerosis 1	Amyotrophic Lateral Sclerosis ALS Lou Gehrig Disease Amyotrophic Lateral Sclerosis Type 1 Charcot Disease ALS1 Amyotrophic Lateral Sclerosis, Susceptibility To Fals Lou Gehrig'S Disease Mnd Motor Neuron Disease Familial Amyotrophic Lateral Sclerosis Amyotrophic Lateral Sclerosis 1, Familial Amyotrophic Lateral Sclerosis 1, Autosomal Dominant Motor Neuron Disease, Bulbar Motor Neurone Disease Amyotrophic Lateral Sclerosis With Dementia Dementia With Amyotrophic Lateral Sclerosis Motor Neuron Disease, Amyotrophic Lateral Sclerosis Sclerosis, Lateral, Amyotrophic Sclerosis, Lateral, Amyotrophic, Type 1 Amyotrophic Sclerosis Als - [Amyotrophic Lateral Sclerosis] Wasting Palsy Amyotrophic Paralysis Amyotrophy Lateral Sclerosis Wasting Paralysis Spinal Progressive Amyotrophy Progressive Atrophic Paralysis
Acute Myelomonocytic Leukemia	Acute Myeloid Leukemia With Abnormal Bone Marrow Eosinophils Inv(16)(P13q22) Or T(16 16)(P13 Q22) Aml M4 Ammol Acute Myeloblastic Leukemia Type 4 Aml With Abnormal Bone Marrow Eosinophils Inv(16)(P13q22) Or T(16 16)(P13 Q22) Aml-M4 Aml With Inv(16)(P13.1q22) Or T(16 16)(P13.1 Q22) Cbfb-Myh11 Leukemia Myelomonocytic Acute Leukemia, Myelomonocytic, Acute Acute Myelomonocytic Leukaemia Without Mention Of Remission Myelomonocytic Leukaemia Nos
Myeloma, Multiple	Multiple Myeloma Plasma Cell Myeloma Kahler Disease Myelomatosis Medullary Plasmacytoma Multiple Myeloma, Resistance To Myeloma Plasma Cell Dyscrasia Kahler'S Disease Multiple Myeloma, Susceptibility To Myeloma - Multiple Kahler-Bozzolo Disease Plasma Cell Myelomas MM Plasma Cell Neoplasm Primary Systemic Amyloidosis Primary Amyloidosis Immunoglobulin Deposition Disease Plasmacytic Myeloma Multiple Myelomata Multiple Myeloma Nos Multiple Myeloma Without Mention Of Remission Monostotic Plasma Cell Myeloma Mm - [Multiple Myeloma]
Prolapse Of Urethra	Urethrocele
Connective Tissue Disease	Connective Tissue Diseases Connective Tissue Disorder Abnormality Of Connective Tissue Disorder Of Connective Tissue Connective Tissue Disorders
Leukemia, Acute Myeloid	Acute Myeloid Leukemia Leukemia, Acute Myelogenous Acute Myelogenous Leukemia AML Leukemia, Acute Myeloid, Susceptibility To Acute Myeloblastic Leukemia Leukemia, Acute Myeloid, Reduced Survival In, Somatic Acute Myeloid Leukaemia Leukemia, Myelocytic, Acute Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome Secondary Aml Acute Myelocytic Leukemia Acute Myeloid Leukemia, Somatic Leukemia, Acute Myeloid, Somatic Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic Acute Myeloblastic Leukaemia Acute Myelogenous Leukaemia Aml - Acute Myeloid Leukemia Acute Myeloid Leukemia With Cebpa Somatic Mutations Aml With Cebpa Somatic Mutations Inherited Acute Myeloid Leukemia Familial Aml Inherited Aml Pure Familial Aml Pure Familial Acute Myeloid Leukemia Secondary Acute Myeloid Leukemia Therapy-Related Aml And Myelodysplastic Syndrome Acute Myeloid Leukemia, Secondary Acute Non-Lymphoblastic Leukemia Acute Non-Lymphocytic Leukemia Acute Biphenotypic Leukemia Acute Undifferentiated Leukemia Acute Myeloblastic Leukaemia With Multilineage Dysplasia Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission Acute Myeloid Leukaemia With Myelodysplasia-Related Features
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-16749	Pexidartinib		99.64%	Yes
HY-16749A	Pexidartinib hydrochloride		99.82%	Yes
HY-12297	Sulfatinib	Inhibitor	99.52%	Unkown

Clinical Phase

Bioactive Molecules (17)

Cat. No.	Product Name	Effect	Purity	Phase
HY-132166	Velzatinib	Inhibitor	99.40%	Phase 3
HY-109190	Seralutinib	Inhibitor	99.94%	Phase 3
HY-145601	Tinengotinib	Inhibitor	99.57%	Phase 3
HY-124526	Chiauranib	Inhibitor	98.97%	Phase 3
HY-153920A	Pimicotinib hydrochloride	Inhibitor	/	Phase 3
HY-D3284	CSF1		/	Phase 3
HY-12768	Sotuletinib	Inhibitor	99.97%	Phase 2
HY-109086	Edicotinib	Inhibitor	99.68%	Phase 2
HY-19772	GSK3117391	Inhibitor	99.40%	Phase 2
HY-159838	Enrupatinib	Inhibitor	98.90%	Phase 2
HY-161025	SYHA1813	Inhibitor	99.46%	Phase 2
HY-136362	ARRY-382	Inhibitor	99.95%	Phase 2
HY-159503A	Segigratinib hydrochloride	Inhibitor	/	Phase 2
HY-114153A	PLX5622 hemifumarate	Inhibitor	99.93%	Phase 1
HY-111787	Elzovantinib	Inhibitor	99.93%	Phase 1
HY-101768	PRN1371	Inhibitor	99.78%	Phase 1
HY-10204	OSI-930		98.33%	Phase 1

Inhibitory Antibodies (6)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99245	Emactuzumab	Inhibitor	97.60%	Phase 3
HY-P990043	Iluzanebart		98.63%	Phase 2
HY-P99452	Axatilimab	Inhibitor	99.59%	Phase 2
HY-P99259	Cabiralizumab	Inhibitor	99.73%	Phase 2
HY-P99368	Lacnotuzumab	Inhibitor	99.9%	Phase 2
HY-P991048	AMG-820	Inhibitor	98%	Phase 2

Pre-clinical Phase

Bioactive Molecules (71)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-114153	PLX5622	Inhibitor	99.95%	Unkown
HY-50905	Dovitinib	Inhibitor	99.88%	Yes
HY-12768A	Sotuletinib hydrochloride	Inhibitor	99.43%	Unkown
HY-153920	Pimicotinib	Inhibitor	99.92%	Unkown
HY-10408	Ki20227	Inhibitor	99.51%	Unkown
HY-101774	CSF1R-IN-1	Inhibitor	98.04%	Unkown
HY-159108	AZ683	Inhibitor	98.57%	Unkown
HY-117244	AZD7507	Inhibitor	99.57%	Unkown
HY-147615	CSF1R-IN-12		98.75%	Unkown
HY-122906	JTE-952	Inhibitor	99.86%	Unkown
HY-152830	Adrixetinib		99.55%	Unkown
HY-126297	c-Fms-IN-10	Inhibitor	98.63%	Unkown
HY-139990	CSF1R-IN-3	Inhibitor	98.10%	Unkown
HY-145809	FASN-IN-5	Inhibitor	99.98%	Unkown
HY-112451	cFMS Receptor Inhibitor II	Inhibitor	99.88%	Unkown
HY-132935	BPR1R024	Inhibitor	98.50%	Unkown
HY-160842	CSF1R-IN-24	Inhibitor	98.10%	Unkown
HY-117273	AZ304	Inhibitor	99.77%	Unkown
HY-119942	c-Fms-IN-8	Inhibitor	99.50%	Unkown
HY-152830A	Adrixetinib TFA		99.82%	Unkown
HY-101526	GENZ-882706	Inhibitor	/	Unkown
HY-13075	c-Fms-IN-3	Inhibitor	98.83%	Unkown
HY-132935A	BPR1R024 mesylate	Inhibitor	/	Unkown
HY-RS03228	CSF1R Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-13493	AC710	Inhibitor	99.57%	Unkown
HY-13496	JNJ-28312141	Inhibitor	/	Unkown
HY-RS16853	Csf1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-101034	CHMFL-ABL/KIT-155		/	Unkown
HY-12768B	Sotuletinib dihydrochloride	Inhibitor	/	Unkown
HY-174366	JMC14	Inhibitor	/	Unkown
HY-10109A	AS-605240 potassium	Inhibitor	/	Unkown
HY-109086A	Edicotinib hydrochloride	Inhibitor	/	Unkown
HY-112446	ST638	Inhibitor	/	Unkown
HY-13496A	JNJ-28312141 hydrochloride	Inhibitor	/	Unkown
HY-144040	CSF1R-IN-4		/	Unkown
HY-144041	CSF1R-IN-5	Inhibitor	/	Unkown
HY-144042	CSF1R-IN-6		/	Unkown
HY-147608	CSF1R-IN-7	Inhibitor	/	Unkown
HY-147609	CSF1R-IN-8	Inhibitor	/	Unkown
HY-147610	CSF1R-IN-9	Inhibitor	/	Unkown
HY-147611	CSF1R-IN-10	Inhibitor	/	Unkown
HY-147616	CSF1R-IN-13		/	Unkown
HY-147617	CSF1R-IN-14		/	Unkown
HY-153012	Axl/Mer/CSF1R-IN-1	Inhibitor	/	Unkown
HY-153243	IACS-9439	Inhibitor	/	Unkown
HY-153277	Axl/Mer/CSF1R-IN-2	Inhibitor	/	Unkown
HY-155001	CSF1R-IN-15	Inhibitor	/	Unkown
HY-155550	CSF1R-IN-17	Antagonist	/	Unkown
HY-157422	CSF1R-IN-19	Inhibitor	/	Unkown
HY-157996	CSF1R-IN-21	Inhibitor	/	Unkown
HY-158050	PXB17	Inhibitor	/	Unkown
HY-158148	CSF1R-IN-23	Inhibitor	/	Unkown
HY-158363	CSF1R-IN-25	Inhibitor	/	Unkown
HY-161084	CSF1R-IN-18	Inhibitor	/	Unkown
HY-162309	CSF1R-IN-20	Inhibitor	/	Unkown
HY-162415	CSF1R-IN-22		/	Unkown
HY-168954	CSF1R-IN-26		/	Unkown
HY-176194	Antifibrotic agent 1		/	Unkown
HY-183569	CSF1R-IN-27	Inhibitor	/	Unkown
HY-183931	NPA101.3	Inhibitor	/	Unkown
HY-187340	CSF1R/c-Kit-IN-1		/	Unkown
HY-187341	CSF1R/c-Kit-IN-2	Inhibitor	/	Unkown
HY-D3217	Ctrl-CSF1		/	Unkown
HY-RS03227	CSF1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS03229	Csf1r Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS03230	Csf1r Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-13493A	AC710 Mesylate	Inhibitor	/	Unkown
HY-164529	SJ-C1044	Inhibitor	98.63%	Unkown
HY-174606	Human IL34 mRNA		/	Unkown
HY-174734	Human CSF1 mRNA		/	Unkown
HY-RS23294	Csf1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Inhibitory Antibodies (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P990125	Anti-Mouse CSF1R/CD115 Antibody (AFS98)		99.38%	Unkown
HY-P990257	Anti-Mouse CSF1 Antibody (5A1)	Inhibitor	96.799%	Unkown
HY-P990849	Anti-CSF1R/CD115 Antibody (2-4A5-4)	Inhibitor	/	Unkown
HY-P991313	PD-360324	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	CSF1	VGNC	VGNC:39652
Macaca mulatta	CSF1	VGNC	VGNC:71513
Bos taurus	CSF1	VGNC	VGNC:27753
Rattus norvegicus	CSF1	RGD	RGD:621063
Mus musculus	CSF1	MGD	MGI:1339753
Felis catus	CSF1	VGNC	VGNC:61214
Others	CSF1	NCBI