1. Protein Tyrosine Kinase/RTK
  2. c-Fms
  3. CSF1R-IN-14

CSF1R-IN-14 is an isoindolinone derivative compound. CSF1R-IN-14 is a potent inhibitor of CSF1R. Colony stimulating factor 1 (CSF-1, also known as macrophage colony stimulating factor, M-CSF) is an important growth factor that controls bone marrow progenitor cells, monocytes, macrophages, and giants. CSF1R-IN-14 has the potential for the research of cancer diseases (extracted from patent WO2019134662A1, compound 1).

For research use only. We do not sell to patients.

CSF1R-IN-14 Chemical Structure

CSF1R-IN-14 Chemical Structure

CAS No. : 2361378-89-2

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Description

CSF1R-IN-14 is an isoindolinone derivative compound. CSF1R-IN-14 is a potent inhibitor of CSF1R. Colony stimulating factor 1 (CSF-1, also known as macrophage colony stimulating factor, M-CSF) is an important growth factor that controls bone marrow progenitor cells, monocytes, macrophages, and giants. CSF1R-IN-14 has the potential for the research of cancer diseases (extracted from patent WO2019134662A1, compound 1)[1].

Molecular Weight

441.45

Formula

C23H22F3N5O

CAS No.
SMILES

CC1=CC(NCC2=CN=C(C=C2)C(F)(F)F)=NC=C1C3=C4CNC(C4=C(C=C3)N(C)C)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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CSF1R-IN-14 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
CSF1R-IN-14
Cat. No.:
HY-147617
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