CSF1R-IN-17
CSF1R-IN-17 (compound 9) is a potent and selective CSF1R antagonist, with an IC50 of 0.2 nM. CSF1R-IN-17 can inhibit osteoclast differentiation.
For research use only. We do not sell to patients.
- CAS No.: 3034870-19-1
- Formula: C20H25N5O2
- Molecular Weight:367.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BaF3 | IC50 |
1.5 μM
Compound: 9
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Antiproliferative activity against BaF3 cells expressing human CSF1R assessed as suppression of cell proliferation incubated for 72 hrs by Cell Titer Glo assay
Antiproliferative activity against BaF3 cells expressing human CSF1R assessed as suppression of cell proliferation incubated for 72 hrs by Cell Titer Glo assay
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[PMID: 37141705] |
Chemical Information
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CAS No. 3034870-19-1
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Molecular Weight 367.44
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Formula C20H25N5O2
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SMILES
OCCC1=CC=C(C2=NC3=C(N(C)CC4CCOCC4)N=CN=C3N2)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CSF1R-IN-17 Related Classifications
HY-155550 Related Classifications
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