Axl/Mer/CSF1R-IN-1
Axl/Mer-IN-1 (Compound 1) is an Axl/Mer receptor tyrosine kinase (Axl/Mer RTK) and CSF1R inhibitor with Kds of <0.1 μM.
For research use only. We do not sell to patients.
- CAS No.: 2394874-60-1
- Formula: C25H24F3N5O5
- Molecular Weight:531.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Axl |
Mer |
Axl/Mer-IN-1 (Compound 1) inhibits cellular Axl activity with an IC50 of <0.5 μM by H1299 Elisa assay. Axl/Mer-IN-1 inhibits cellular CSF1R activity with IC50s of <0.5 μM and <1.0 μM by THP-1 Elisa assay and by M-NFS-60 viability assay, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2394874-60-1
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Molecular Weight 531.48
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Formula C25H24F3N5O5
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SMILES
O=C(C1=NN(CC)C(C)=C1OCC(F)(F)F)NC2=NC=C(C=C2)OC3=C4C=C(OC)C(OC)=CC4=NC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Axl/Mer/CSF1R-IN-1 Related Classifications
HY-153012 Related Classifications
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