CSF1R-IN-10
CSF1R-IN-10 (Compound 48) is a CSF-1R inhibitor with an IC50 of 0.005 μM.
For research use only. We do not sell to patients.
- CAS No.: 2765301-88-8
- Formula: C25H22N4O3
- Molecular Weight:426.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
CSF-1R[1]
In Vitro
CSF1R-IN-10 (Compound 48) inhibits CSF-1R phosphorylation activity with an IC50 of 0.005 μM in THP-1 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 2765301-88-8
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Molecular Weight 426.47
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Formula C25H22N4O3
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SMILES
CN1C=C(C=N1)C2=NC=CC(OC3=CN=C4O[C@@H](COC4=C3)C5=CC=C(C=C5)C6CC6)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CSF1R-IN-10 Related Classifications
HY-147611 Related Classifications
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