CSF1R-IN-12
Based on 1 Customer Validation
CSF1R-IN-12 (compound 1) is a potent inhibitor of CSF1R. Colony stimulating factor 1 (CSF-1, also known as macrophage colony stimulating factor, M-CSF) is an important growth factor that controls bone marrow progenitor cells, monocytes, macrophages, and giants. CSF1R-IN-12 has the potential for the research of cancer diseases.
For research use only. We do not sell to patients.
- Purity: 98.75%
- CAS No.: 2361556-35-4
- Formula: C21H17F3N4O
- Molecular Weight:398.38
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
Chemical Information
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CAS No. 2361556-35-4
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Appearance Solid
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Molecular Weight 398.38
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Formula C21H17F3N4O
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Color White to off-white
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SMILES
CC1=CC(NCC2=CN=C(C=C2)C(F)(F)F)=NC=C1C3=CC=CC4=C3CNC4=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (251.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5102 mL | 12.5508 mL | 25.1017 mL | 62.7542 mL |
| 5 mM | 0.5020 mL | 2.5102 mL | 5.0203 mL | 12.5508 mL | |
| 10 mM | 0.2510 mL | 1.2551 mL | 2.5102 mL | 6.2754 mL | |
| 15 mM | 0.1673 mL | 0.8367 mL | 1.6734 mL | 4.1836 mL | |
| 20 mM | 0.1255 mL | 0.6275 mL | 1.2551 mL | 3.1377 mL | |
| 25 mM | 0.1004 mL | 0.5020 mL | 1.0041 mL | 2.5102 mL | |
| 30 mM | 0.0837 mL | 0.4184 mL | 0.8367 mL | 2.0918 mL | |
| 40 mM | 0.0628 mL | 0.3138 mL | 0.6275 mL | 1.5689 mL | |
| 50 mM | 0.0502 mL | 0.2510 mL | 0.5020 mL | 1.2551 mL | |
| 60 mM | 0.0418 mL | 0.2092 mL | 0.4184 mL | 1.0459 mL | |
| 80 mM | 0.0314 mL | 0.1569 mL | 0.3138 mL | 0.7844 mL | |
| 100 mM | 0.0251 mL | 0.1255 mL | 0.2510 mL | 0.6275 mL |