Kit-IN-3

Kit-IN-3 is a KIT inhibitor with an IC50 of 2.4 nM. Kit-IN-3 targets the wild-type receptor tyrosine kinase, blocks SCF-mediated autophosphorylation, and reduces cellular activity in serum. Kit-IN-3 inhibits the off-target class III receptor tyrosine kinase PDGFRα with an IC50 of 97 nM, is selective for PDGFRα and PDGFRβ, and has no activity against CSF1R and FLT3.

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  • Fòrmula: C21H17F2N5O2
  • Peso molecular:409.39
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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