1. Protein Tyrosine Kinase/RTK
  2. c-Fms
  3. c-Fms-IN-12

c-Fms-IN-12 

Cat. No.: HY-136362
Handling Instructions

c-Fms-IN-12 is a c-Fms inhibitor extracted from patent WO2011079076A1, Compound Example 65, has an IC50 of 93.6-283.7 nM.

For research use only. We do not sell to patients.

c-Fms-IN-12 Chemical Structure

c-Fms-IN-12 Chemical Structure

CAS No. : 1313407-95-2

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Description

c-Fms-IN-12 is a c-Fms inhibitor extracted from patent WO2011079076A1, Compound Example 65, has an IC50 of 93.6-283.7 nM[1].

IC50 & Target

c-Fms[1]

In Vitro

cFMS, a type III receptor tyrosine kinases, which are useful in the treatment of bone-related diseases, cancer, autoimmune disorders, inflammatory diseases, cardiovascular diseases and pain[1].

Molecular Weight

564.68

Formula

C₃₂H₃₆N₈O₂

CAS No.

1313407-95-2

SMILES

O=C(C1=CN=C2C=C(OCCN3CCN(C)CC3)C=CN21)NC4=CC=CC5=C4C(C6CC6)=NN5CC7=NC(C)=CC=C7

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

c-Fms-IN-12c-FmsCSF-1 receptorcolony stimulating factor 1 receptorCSF-1RCSF1Rtyrosinekinasesbone-relateddiseasescancerautoimmune disordersinflammatorycardiovascularpainInhibitorinhibitorinhibit

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