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Cat. No.: HY-P86586

Ctip2 Antibody (YA6278)

Name: Ctip2 Antibody (YA6278)
Brand: MedChemExpress
SKU: HY-P86586
Availability: PreOrder

Ctip2 Antibody (YA6278) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Ctip2.

For research use only. We do not sell to patients.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	IHC-P IHC-P: Immunohistochemistry-Paraffin	WB WB: Western Blot	ICC/IF ICC/IF: Immunocytochemistry/ Immunofluorescence	ELISA ELISA: Enzyme Linked Immunosorbent Assay	IP IP: Immunoprecipitation
Dilution Ratio	1:200-1000	1:1000-5000	1:200-1000	1:5000-20000	1:50-200

Description

Ctip2 Antibody (YA6278) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Ctip2.

Host Rabbit
Clonality Monoclonal
Species Reactivity
Human, Mouse, Rat
Observed Molecular Weight

Observed band size: 96 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 96 kDa

Purification

Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

Ctip2 is key regulator of both differentiation and survival of T-lymphocytes during thymocyte development in mammals. Essential in controlling the responsiveness of hematopoietic stem cells to chemotactic signals by modulating the expression of the receptors CCR7 and CCR9, which direct the movement of progenitor cells from the bone marrow to the thymus. Is a regulator of IL2 promoter and enhances IL2 expression in activated CD4(+) T-lymphocytes. Tumor-suppressor that represses transcription through direct, TFCOUP2-independent binding to a GC-rich response element. May also function in the P53-signaling pathway^[1]^[2].
Subcellular Localization

Nucleus
Expression

Tissue_specificity:Highly expressed in brain tissue and malignant T cell lines derived from adult T-cell leukemia/lymphoma.
Isoforms & Post-Translational Modification

Q9C0K0 has 2 isomers: Q9C0K0-1: 95519 Da (predicted); Q9C0K0-2: 88476 Da (predicted).
Sumoylated with SUMO1
Subunit

Interacts with TFCOUP1, SIRT1, ARP1 and EAR2 (By similarity). Interacts with EP300; the interaction is detected in activated T-lymphocytes, but not under resting conditions (PubMed:27959755)
SwissProt ID

Q9C0K0
Gene ID

64919 [NCBI]