CYP2E1 Antibody (YA7326)
CYP2E1 Antibody (YA7326) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CYP2E1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF
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Formulation:
Supplied in 0.01M tris buffered saline (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:50-200 |
Product Details
CYP2E1 Antibody (YA7326) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CYP2E1.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Calculated Molecular Weight Predicted band size: 57 kDa;
KLH conjugated synthetic peptide derived from human CYP2E1
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 0.01M tris buffered saline (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CYP2E1 is an A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics (Probable)[1][2].
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Subcellular Localization
Endoplasmic reticulum membrane,Microsome membrane,Mitochondrion inner membrane
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Expression
Induction: By ethanol and isoniazid
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Isoforms & Post-Translational Modification
P05181: 493 amino acids, molecular weight 56849 Da.
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Subunit
Interacts with chaperones HSP70 and HSP90; this interaction is required for initial targeting to mitochondria
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SwissProt ID
Documentation
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