Cytochrome C Antibody (YA5422)
(Synonyms: CYCS; CYC; Cytochrome c)Cytochrome C Antibody (YA5422) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Cytochrome C.
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Host:
Mouse
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Application:
WB, ICC/IF, IHC-P
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Reactivity :
Human, Mouse, Rat, Chicken
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Formulation:
Supplied in PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-5000 | 1:500-1000 | 1:200 |
Product Details
Cytochrome C Antibody (YA5422) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Cytochrome C.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat, Chicken
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Observed Molecular WeightObserved band size: 14 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Recombinant Protein of CYCS
affinity chromatography.
Non-conjugated
Unmodified
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Cytochrome C is an Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain; Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases
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Subcellular Localization
Mitochondrion intermembrane space
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SwissProt ID
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Synonyms
CYCS; CYC; Cytochrome c
Documentation
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