DEF8 Antibody (YA8456)
(Synonyms: FLJ20186; MGC104349)DEF8 Antibody (YA8456) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to DEF8.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
IHC-P, ICC/IF, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100-250 | 1:100 |
Product Details
DEF8 Antibody (YA8456) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to DEF8.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 58.5 kDa
Full length human recombinant protein of human DEF8 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DEF8 is a Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. Involved in bone resorption
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Isoforms & Post-Translational Modification
Q6ZN54 has 6 isomers: Q6ZN54-1: 58710 Da (predicted); Q6ZN54-2: 22976 Da (predicted); Q6ZN54-3: 51222 Da (predicted); Q6ZN54-4: 45388 Da (predicted); Q6ZN54-5: 52281 Da (predicted); Q6ZN54-6: 50161 Da (predicted).
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Subunit
Interacts (via C-terminus) with PLEKHM1; this interaction is weak but increased in a RAB7A-dependent manner
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SwissProt ID
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Synonyms
FLJ20186; MGC104349
Documentation
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