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  4. Monoclonal Antibodies
  5. DLL4 Antibody (YA7088)(PBS only)

DLL4 Antibody (YA7088)(PBS only)

Cat. No.: HY-P87400A
User Guide for Antibodies Technical Support

DLL4 Antibody (YA7088) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DLL4.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

DLL4 Antibody (YA7088) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DLL4.
Host

Mouse
Molecular Weight

Predicted band size: 74.6kDa;
Species Reactivity
Human
SwissProt ID
Immunogen

Purified recombinant fragment of human DLL4 expressed in E. Coli.
Application &
Dilution Ratio
Application Dilution Ratio
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:200-1000
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
1:10000
Purity affinity purified. Conjugation Non-conjugated
Isotype IgG2b  
Appearance

Solution
Formulation

Supplied in PBS, pH 7.4.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate (PubMed:17728344)
Subcellular Localization：Cell membrane
Expression：
Tissue_Specificity: Expressed in vascular endothelium
Isoforms & Post-Translational Modification：Q9NR61: 685 amino acids, molecular weight 74605 Da.
Subunit：Interacts with NOTCH4
Synonyms
UNQ1895/PRO4341, DLL4, Delta-like protein 4, Drosophila Delta homolog 4, Delta4
Documentation
User Guide for Antibodies (1077 KB)

DLL4 Antibody (YA7088)(PBS only) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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DLL4 Antibody (YA7088)(PBS only)
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