DOCK2 Antibody (YA8613)(PBS only)

製品番号: HY-P88929A: データシート User Guide for Antibodies
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DOCK2 Antibody (YA8613) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to DOCK2.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明
参考文献

製品説明

DOCK2 Antibody (YA8613) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to DOCK2.

Host

Mouse

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q92608

Immunogen

Human recombinant protein fragment corresponding to amino acids 1544-1830 of human DOCK2 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250

純度	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG2a

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2

Subcellular Localization：Endomembrane system,Cytoplasm, cytoskeleton

Expression：
Tissue_Specificity: Specifically expressed in hematopoietic cells. Highly expressed in peripheral blood leukocytes, and expressed at intermediate level in thymus and spleen. Expressed at very low level in the small intestine and colon

Isoforms & Post-Translational Modification：Q92608 has two isomers: Q92608-1: 211948 Da (predicted); Q92608-2: 38461 Da (predicted).

Subunit：Homodimer (Probable)

Synonyms

FLJ46592; KIAA0209

ドキュメンテーション

User Guide for Antibodies (1077 KB)

参考文献

[1]. /biology-dictionary/rko-cell.html [Content Brief]