DOK7 Antibody (YA7945)

Cat. No.: HY-P88261: Ficha de datos User Guide for Antibodies
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DOK7 Antibody (YA7945) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DOK7.

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Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn
Referencias

Descripciòn

DOK7 Antibody (YA7945) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DOK7.

Host

Mouse

Clonality

Monoclonal

Peso molecular

Predicted band size: 52.9 kDa

Species Reactivity

Human, Mouse

SwissProt ID

Q18PE1

Immunogen

Full length human recombinant protein of human DOK7 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Pureza	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK

Subcellular Localization：Cell membrane,Synapse

Expression：
Tissue_Specificity: Preferentially expressed in skeletal muscle and heart. Present in thigh muscle, diaphragm and heart but not in the liver or spleen (at protein level)

Isoforms & Post-Translational Modification：Q18PE1 has four isomers: Q18PE1-1: 53097 Da (predicted); Q18PE1-2: 37161 Da (predicted); Q18PE1-4: 27514 Da (predicted); Q18PE1-3: 63938 Da (predicted).

Subunit：Homodimer (By similarity)

Synonyms

C4orf25; CMS1B; CMS10

Documentación

User Guide for Antibodies (1077 KB)

Referencias

[1]. /biology-dictionary/pbmc-cell.html [Content Brief]