DOK7 Antibody (YA7945)
(Synonyms: C4orf25; CMS1B; CMS10)DOK7 Antibody (YA7945) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DOK7.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ICC/IF, FC
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Reactivity :
Human, Mouse
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100-250 | 1:100 |
Product Details
DOK7 Antibody (YA7945) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DOK7.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse
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Calculated Molecular Weight Predicted band size: 52.9 kDa
Full length human recombinant protein of human DOK7 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DOK7 is a Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK
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Subcellular Localization
Cell membrane,Synapse
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Expression
Tissue_Specificity: Preferentially expressed in skeletal muscle and heart. Present in thigh muscle, diaphragm and heart but not in the liver or spleen (at protein level) -
Isoforms & Post-Translational Modification
Q18PE1 has four isomers: Q18PE1-1: 53097 Da (predicted); Q18PE1-2: 37161 Da (predicted); Q18PE1-4: 27514 Da (predicted); Q18PE1-3: 63938 Da (predicted).
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Subunit
Homodimer (By similarity)
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SwissProt ID
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Synonyms
C4orf25; CMS1B; CMS10
Documentation
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