DPH2 Antibody (YA8482)
(別名: DPH2L2)DPH2 Antibody (YA8482) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DPH2.
-
Host:
Mouse
-
Isotype:
IgG1
-
Application:
IHC-P, ICC/IF, FC
-
Reactivity :
Human, Rat
-
Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
-
Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
|
|---|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100-250 | 1:100 |
Product Details
DPH2 Antibody (YA8482) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DPH2.
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityHuman, Rat
-
Calculated Molecular Weight Predicted band size: 51.9 kDa
Full length human recombinant protein of human DPH2 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
-
Appearance
Liquid
-
Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
輸送条件
Shipping with blue ice.
Background
-
Function
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2 (PubMed:32576952). DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase (By similarity). Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit (By similarity)
-
Expression
Tissue_Specificity: Strongly expressed in skeletal muscle. Moderately expressed in heart, small intestine, liver, pancreas, testis and colon. Weakly expressed in brain, placenta, kidney, spleen, thymus, prostate, ovary and lymphocytes -
Isoforms & Post-Translational Modification
Q9BQC3 has three isomers: Q9BQC3-1: 52083 Da (predicted); Q9BQC3-2: 27529 Da (predicted); Q9BQC3-3: 38510 Da (predicted).
-
Subunit
Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase (By similarity)
-
SwissProt ID
-
別名
DPH2L2
ドキュメント
Powered by Bioz
